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Adv. Pharm NURS 8024 Week 1 with Complete Solutions

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Adv. Pharm NURS 8024 Week 1 with Complete SolutionsAdv. Pharm NURS 8024 Week 1 with Complete SolutionsAdv. Pharm NURS 8024 Week 1 with Complete SolutionsAdv. Pharm NURS 8024 Week 1 with Complete Solutions Pharmacokinetics - ANSWER - what the body does to the drug Pharmacodynamics - ANSWER - wha...

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  • September 16, 2024
  • 14
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • Adv. Pharm NURS 8024
  • Adv. Pharm NURS 8024
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NursingTutor1
Adv. Pharm NURS 8024 Week 1
with Complete Solutions
Pharmacokinetics - ANSWER - what the body does to the drug


Pharmacodynamics - ANSWER - what the drug does to the body


Toxicology - ANSWER - The undesirable effects of chemicals on living systems


Pharmacotherapeutics - ANSWER - dynamic that achieves the desired therapeutic
effect of the drug without causing other undesirable effects


Legend drugs - ANSWER - another name for prescription drugs


Pharmacogenomics - ANSWER - the study of genetically determined variations in
the response to drugs


Pharmacologic Agonist - ANSWER - agent binds to and activates the
receptor - directly or indirectly causing an effect, full or partial agonists


Pharmacological Antagonist - ANSWER - Agent binds to receptor-completes with
other molecules and prevents binding by other molecules-it inhibits other molecules
from binding


Pro-drug - ANSWER - An inactive percursor chemical-must be abosorbed and
distributed and converted to the active form of the drug by biologic processes.
Rectal Route of administration - ANSWER - 50% of circulatory drainage BYPASSES
portal circulation
Meaning: Less first pass effect


Drug Transport Methods: - ANSWER - Passive diffusion (no E needed)

, Active transport (requires E)
Endocytosis


Passive diffusion (simple diffusion) - ANSWER - no energy needed, related to
concentration gradient across membrane, HIGHER concentration goes to LOWER
concentration


What is ADME? - ANSWER - Absorption
Distribution
Metabolism
Elimination


Absorption - ANSWER - entry of pharmacologic agent into plasma


Distribution - ANSWER - agent leaves the bloodstream and distributes to interstitial
and intracellular fluids


Metablosim - ANSWER - chemical processes that occur to make the drug useful in
the bloodstream--done by the liver, kidney, or other tissue


Ellimination - ANSWER - Leaving the body-via urine, bile, feces, lungs, sweat, breast
milk


2 Major Administration Routes - ANSWER - 1. Enteral -most common, easy, cheap-
BUT drug absorption pathways can be complicated
2. Parenteral-IV, fast, more expensive, once in-cannot get back


Enteral drug administration - ANSWER - oral, sublingual, rectal
drug absorption pathways complicated
**First-pass metabolism can limit the amount of drug that enters systemic
circulation
influenced by food and other drugs

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