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PMCOL 200 – Hallucinogens Exam Questions With Correct Answers

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PMCOL 200 – Hallucinogens Exam Questions With Correct Answers What are the 3 monoamine neurotransmitters? - answerserotonin, norepinephrine, and dopamine What are the 4 ways that drugs can manipulate monoamine neurotransmitters? - answer1 - increasing release 2 - blocking reuptake 3 - inhi...

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  • September 17, 2024
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PMCOL 200 – Hallucinogens Exam
Questions With Correct Answers


What are the 3 monoamine neurotransmitters? - answer✔serotonin, norepinephrine, and
dopamine

What are the 4 ways that drugs can manipulate monoamine neurotransmitters? - answer✔1 -
increasing release
2 - blocking reuptake
3 - inhibiting metabolism
4 - activating a receptor

What are the receptors for serotonin called? How many subtypes are there? - answer✔5-HT
receptors


There are 7 subtypes

What are the receptors for dopamine called? - answer✔D1 and D2

What are the receptors for norepinephrine called? - answer✔alpha and beta adrenergic
receptors

What enzyme metabolizes (breaks down) all monoamines? - answer✔monoamine oxidases
(MAO)

What amino acid is serotonin made from? - answer✔Tryptophan

What amino acid is dopamine made from? - answer✔Tyrosine

What amino acid is norepinephrine made from? - answer✔Tyrosine, but it must be converted
into dopamine first.
What is the only 5HT receptor that doesn't activate a G protein signalling cascade? -
answer✔5HT-3

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What 2 monoamine receptors positively modulate the PLC (Gq) pathway? - answer✔5HT-2
(serotonin)
Alpha 1 (NE)

What 4 monoamine receptors inhibit the AC pathway (are Gi)? - answer✔5HT-1 & 5
(serotonin)
Alpha 2 (NE)
D2 (dopamine)

What 5 monoamine receptors activate the AC pathway (are Gs)? - answer✔5HT-4, 6 & 7
(serotonin)
Beta (NE)
D1 (dopamine)
What are the 3 transporters that are responsible for reuptake of monoamines back into the
presynaptic terminal? What does each move? - answer✔•NET: norepinephrine
•DAT: dopamine
•SERT: serotonin
What pumps cytosolic neurotransmitters into vesicles to be released back into the synapse
following action potential? - answer✔vesicular monoaminergic transporter (VMAT)

LSD - answer✔lysergic acid diethylamide

What is another name for LSD? - answer✔acid

Who first isolated LSD? - answer✔Dr. Albert Hofmann

What was LSD originally isolated from? - answer✔ergot, a fungus that grows on rye.


The LSD awe have today is a form that is more stable in water.

What are the effects of LSD? - answer✔dilated pupils, increased heart rate and blood pressure
and hallucinations

What are the adverse psychological effects of LSD? - answer✔anxiety, paranoia, delusions and
HPPD

Hallucinogen persisting perception disorder (HPPD) - answer✔distressing visual hallucinations
that appear following drug use

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