PMCOL 343: Pain I Exam Questions With Correct Answers
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Course
PMCOL 343
Institution
PMCOL 343
PMCOL 343: Pain I Exam Questions With
Correct Answers
What type of perception do A-beta fibres play a crucial role in - answerPerception of light
touch; these fibres are highly sensitive to light touch and convey information about tactile
sensations
Describe the extent of myelination of A-beta...
PMCOL 343: Pain I Exam Questions With
Correct Answers
What type of perception do A-beta fibres play a crucial role in - answer✔Perception of light
touch; these fibres are highly sensitive to light touch and convey information about tactile
sensations
Describe the extent of myelination of A-beta fibres - answer✔Heavily myelinated
What type of perception do A-delta fibres play a crucial role in - answer✔Perception of signals
related to sharp and acute pain
Describe the extent of myelination of A-delta fibres - answer✔Myelinated, but less than A-beta
fibres
What type of perception do C fibres play a crucial role in - answer✔Perception of dull,
persistent pain signals (heat and chemical stimuli)
Describe the extent of myelination of C fibres - answer✔Unmyelinated
Rank A-beta, A-delta, and C fibres from slowest impulse conduction to fastest impulse
conduction - answer✔C fibres (slowest), A-delta fibres, A-beta fibres (fastest)
Where are the cell bodies for A-beta, A-delta, and C fibres located - answer✔In the dorsal root
ganglion
These sensory neurons have long projections that extend into what two direction - answer✔One
projection extending to peripheral tissues to detect sensory stimuli, and the other extending into
the spinal cord
When a painful stimulus is present, what type of receptor in the peripheral tissue is activated, and
what happens when these are activated - answer✔Nociceptors; when activated they generate
action potentials
The action potentials caused by nociceptor activation is then travelled along through pain fibres
to what location - answer✔The dorsal root ganglion
The sensory information from the dorsal root ganglion enters the spinal cord through what type
of neurons - answer✔Dorsal root projecting neurons
What happens to the pain signal once it is in these higher brain centres - answer✔Pain signal is
processed and interpreted, leading to the conscious perception of pain
What is the definition of nociception - answer✔The neural encoding of a noxious signal
What is the definition of pain - answer✔The unpleasant experience associated with tissue
damage; more psychological (how that nociception affects you)
What is the definition of an analgesic - answer✔Selectively blocks the sensation of pain,
without blocking other modalities
What is the definition of a local anesthetic - answer✔Blocks nerve conduction and all sensation
in a localized area
What is the definition of a general anesthetic - answer✔Induces a reversible loss of
consciousness
General anesthetics do not always cause analgesia; describe what this means -
answer✔Provides for intraoperative analgesia, but additional measures are usually required for
postoperative analgesia
What is the definition of hyperalgesia - answer✔The enhanced response to a painful stimuli
What is the definition of allodynia - answer✔The generation of a painful response by what is
considered an innocuous stimulus (generation of pain from a non-painful stimuli)
Describe what the term 'good pain' refers to - answer✔The pain response is important for our
existence, as it serves a protective function and biological purpose (ie. protection from tissue
damage)
Acute pain is generally carried by A-delta fibres; what fibres would carry the information if the
injury led to more persistent pain - answer✔Would be carried by C-fibres
What is the most common treatment for mild, musculoskeletal pain - answer✔Typically with
non-steroidal anti-inflammatory drugs (like aspirin or ibuprofen)
Persistent pain is caused mainly by the release of what three inflammatory mediators -
answer✔Bradykinin, histamine acid metabolites, and prostaglandins
What does the term 'deep pain' refer to - answer✔Pain that originates from structures located
deeper within the body, as opposed to pain from superficial tissues
What is the most common treatment for deep pain - answer✔With the use of major analgesics,
such as morphine (an opioid)
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