PT of gemfibrozil
-decrease triglycerides
-increase HDL
-can increase or decrease LDL
PD of heparin and enoxaparin
inhibits thrombin and factor Xa to suppress fibrin formation
antidote of heparin and enoxaparin
protamine sulfate
antidote of warfarin
vitamin K
PD of alteplase
breaks up clots by activating all plasmin in body
PD of clopidrogrel
causes irreversible receptor blockage to decrease clotting
PK of furosemide
potent in IV for CHF and pulmonary edema
which of the beta-2 agonists is used as a rescue drug?
albuterol- used for acute attacks
should you administer a SABA before or after the glucocorticoid inhaler?
administer the SABA to open the airways and then the glucocorticoid to decrease inflammation
,AE of prednisone and methylprednisone
-immunosuppression
-ulcers
-hyperglycemia
-osteoporosis
nursing intervention for prednisone and methylprednisone
-wean slowly to prevent adrenal insufficiency
-use alternate day dosing
AE of morphine and codeine
-N/V
-constipation
-respiratory depression
antidote of morphine and codeine
naloxone (Narcan)
4 contras of ibuprofen
-ulcers
-GI bleed
-surgery
-other NSAIDs or glucocorticoids
PT of aspirin
-mild to moderate pain
-also has antiplatelet effects
toxicity s/s for aspirin
-tinnitus
-drowsy
-confusion
-increased RR
AE of acetaminophen
very safe and approx no contra's or AE
, PD of acetaminophen
inhibits prostaglandins (fever) in the CNS + does not affect platelets
antidote for acetaminophen
acetylcysteine
characteristics of rheumatoid arthritis
-morning stiffness
-bilateral pain
characteristics of gout
increased uric acid in body that crystallizes in joints to cause pain and swelling
nursing interventions for allopurinol and cholchicine
increase fluids and decrease protein intake
PT of allopurinol
#1 for chronic gout (take everyday)
PT of cholchicine
#1 for acute gout attack (take it when attack starts and stop it after attack)
PT of acyclovir
herpes or varicella-zoster
AE of acyclovir
nephrotoxicity so decrease dose in renal-impaired
PK of amphotericin B
vesicant so use a central line
PK of vancomycin
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