NRSG 540 Exam 1 With Questions And 100% ALL SURE ANSWERS
Terms in this set (100)
Therapeutic: organization on the basis of what the drug is meant to alleviate.
Basis for Therapeutic Classification
Example: Anticoagulant, Antihypertensive
Basis for Pharmacologic Classification Organization of a drug based on the way it works on the molecular, tissue, or body system level
Both are useful, but sometimes it would be necessary to exclude certain drugs because of how
Explain the basis for placing drugs into
they work on the molecular level.
therapeutic and pharmacologic classes.
Example: Aspirin and Reye's Syndrome in children
Describe what is meant by a drug's mechanism of How a drug produces its physiologic effects
action.
- Name established by the IUPAC
- Precise and only one name per drug
Drug Chemical Name
- Often complicated and difficult name to pronounce
- Occasionally classified by only part of chemical structure
- Brand or Proprietary name (starts with uppercase letter); Drug manufacturer gets a 7 year
Drug Trade Name patent
- Short and Easy names
NRSG 540 Exam 1
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, - Assigned by the USAN council
- Less complicated than Chemical names
Drug Generic Name - Recognized and used by many large health organizations
- Only one Generic Name
- Bio-similar drugs are always followed by 4 lowercase letters Example: infleximab-abda
Generic Name:
- Is a stand alone active ingredient
- Drug name is usually lowercase
Explain the differences between trade name Trade Name:
drugs and their generic equivalents. - Can contain more than one active generic ingredient
- Trade names are capitalized
- Key difference may be in the bio-availability of the drug I.E. how well it works
- movement of drug from site of administration into the blood
- Primary factor influencing how long it takes a drug to produce its effect
Drug Absorption
- Route of administration effects the speed of onset
- Lipid Solubility is faster than water Solubility
Drug Onset - the time it takes for the drug to elicit a therapeutic response
Drug Peak - highest concentration in blood
- the process of eliminating medications, usually through the kidneys in urine, but also through
Drug Excretion sweat, feces, and saliva
- Kidney is the primary site
- the length of time required for the plasma concentration of a medication to decrease by one-
Plasma Half Life
half after administration
- a drug that will bind to a receptor on a cell and trigger a response by the cell, generally
mimicking the response or action of a naturally occurring substance
Drug Agonist
- Ex: Albuterol (Ventolin)
Drug Antagonist - a drug that blocks another drug from combining with a receptor
Drug Potency - More Potent = Therapeutic effect at lower dose
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