NUR 243 Test 4 URI Questions and
Correct Answers
Trimethoprim/Sulfamethoxazole ✅MOA- inhibits tetrahydrofolic acid, gram - and +
TE- UTI, pneumonia, GI infections, otitis media, bronchitis, salmonella
AE- nausea, Steven-johnson syndrome, rash, vomiting
DI- intensifies warfarin
Fluroquinolones (ciprofloxacin) ✅MOA- inhibits bacteria, bactericidal, gram - and +
TE- respiratory infections, UTI, GI, bones, joints, soft tissue
AE- dizziness, headache, confusion, tendon rupture, phytotoxicity, increased risk of
c.diff, candida infections
DI- absorption reduced by aluminum, magnesium, dairy. Elevates warfarin, theophylline,
and tinidazole
Metronidazole (Flagyl) ✅MOA- narrow, bactericidal, -/+ but anaerobes only
TE- protozoal infections/anaerobe infections, H.plyori, c.diff, yeast infections, sugerical
infections
AE- neurotoxicity, superinfection, allergy, metallic taste
DI- alcohol
Benzodiazepines (lorazepam) ✅MOA- intensifies effects of GABA, inhibits neuro
excitability
TE- anxiety, insomnia, seizures
AE- CNS depression, anterograde, sleep driving, respiratory depression
DI- harmful when used with other depressants
Benzodiazepines-like (zolpidem) ✅MOA- intensifies GABA and decreases
neuroexcitabilty
TE- short-term management of insomnia
AE- day time dizziness/ drowsiness
DO- amplified if taken with other depressants
Ramelteon ✅MOA- agonist on melatonin receptors
TE- induces sleep, does not maintain, rapid onset, short duration
AE- dizziness/fatigue, allergic reactions
DI- avoid alcohol, fluvoxamine
Pure opioid agonists (morphine) ✅MOA- agonist to kappa and mu receptor, slow to
cross BBB, extensive first pass effect
TE- analgesic, euphoria/tranquility