Midterm Exam Nr565 Advanced
Pharmacology Care Of The Fundamentals
Exam Updated 2024 (Chamberlain)
what medication can be added for patients with
worsening symptoms of HF? - ✔️CORRECT ANSWER✅-
aldosterone antagonist- promotes myocardial
remodeling and fibrosis, help with symptoms
When is it used - ASCVD Risk Score - ✔️CORRECT
ANSWER✅-In children a screening should be done
between ages 9 and 11 and then again at ages 19 and 21.
For adults every 5 years after the age of 20. Some people
are at greater risk like those with diabetes and a risk
score greater than 7.5% and should be screened more
often
ezetimibe- when can it be used? - ✔️CORRECT
ANSWER✅-Cholesterol Absorption Inhibitor- lowers
cholesterol levels by decreasing the amount of
cholesterol that is absorbed from the small intestine, so
,that there is less intestinal cholesterol delivered to the
liver. Does not affect triglycerides
Colchicine should not be taken with what medications? -
✔️CORRECT ANSWER✅-statins, CYP3A4 inhibitors
Methadone can be used for which two therapies? -
✔️CORRECT ANSWER✅-maintenance- transferring
addict from abuse opioid to oral methadone suppressive-
prevent the reinforcing effects of opioid induced
euphoria
Methadone half life? - ✔️CORRECT ANSWER✅-long,
prescribed only by providers with special training in pain
management
Does methadone or buprenorphine have a ceiling (drugs
that impact on body plateus) to respiratory depression? -
✔️CORRECT ANSWER✅-buprenorphine - makes it safer
What are the therapeutic uses for morphine? -
✔️CORRECT ANSWER✅-pain management, sedation,
,euphoria, respiratory depression, cough suppression,
reduces anxiety, a sense of well-being, suppress GI
motility (help with severe diarrhea)
Therapeutic uses of fentanyl? - ✔️CORRECT
ANSWER✅-Chronic or acute severe pain, cancer pain
Risk factors for opioid use disorder - ✔️CORRECT
ANSWER✅-chronic pain, family history, other substance
abuse, prescribed for long term use
Drugs not safe to take with opioids - ✔️CORRECT
ANSWER✅-opioids, benzos, alcohol, CNS depressants,
anti-histamines, general anesthetics
Buprenorzhine and Naloxone - ✔️CORRECT ANSWER✅-
agonist-antagonist
Buprenorzhine and Naloxone benefit of combination -
✔️CORRECT ANSWER✅-Naloxone is added to
, buprenorphine to decrease the likelihood of diversion
and misuse of the combination drug product
: Treatment of chronic pain- Example: How should
something like osteoarthritis be treated? - ✔️CORRECT
ANSWER✅-Non Opioid medications - NSAIDs, cox-2
inhibitors Nonpharmacologic tx - heat/cold, yoga,
physical therapy, exercise, healthy weight
When prescribing medication we must understand that
liver function declines with age due to what cause? a.
enlarged liver b. decreased blood flow to liver c.
increased activity of the hepatic enzymes - ✔️CORRECT
ANSWER✅-decreased blood flow to liver a. decreased
liver mass c. decrease in enzyme activity
What is the most important cause of adverse drug
reactions? (older age) a. high drug dosages b. lack of
monitoring medications c. decreased renal excretion d.
overprescribing/polypharmacy - ✔️CORRECT
ANSWER✅-decreased renal excretion
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