1. Chapter 1
a. Four basic terms
i. Drug: any chemical that can affect living processes
ii. Pharmacology: the study of drugs and their interactions with living
systems
iii. Clinical pharmacology: The study of drugs in humans
iv. Pharmaco-therapeutics: the use of drugs to diagnose prevent or treat
disease
b. 3 most important properties of an IDEAL drug
i. first; no drug is ideal
ii. Effectiveness: most important property a drug can have
iii. Safey: drug cannot produce harmful effects
iv. Selectivity: drug elecits only the response for which it is given
v. You would also want reversible effects and ease of administration
c. Factors that determine the intensity of drug responses
i. Administration
ii. Pharmokinetics- bodies impact on the drug
iii. Pharmodynamics- drugs impact on the body
iv. Sources of individual variations
2. Chapter 2 Evolution of nursing responsibilities regarding drugs
a. A. Nurses must know
i. What meds are appropriate for the patient
ii. What drugs contraindicated for the PT
iii. Probable consequences of the interactions between the drug and PT
b. Nurses role as an advocate
i. The last line of defense for the pt
ii. Ethically and legally unacceptable to administer a drug that is harmful
to the pt, even though the medication has been prescribed
1. Nurses must participate in a system of checks and balances to
promote beneficial effects and to minimize harm to pts
iii. Right drug
iv. Right patient
v. Right dose
vi. Right time
vii. Right assessment
viii. Right documentation
ix. Right evaluation
x. Right of patient to education
xi. Right of patient to refuse care
c. Two major areas in which pharmacologic knowledge can be applied
, i. Pt care
ii. Pt education
d. PT EDUCATION
e. Application pharmacology in pt care
i. Preadministration assessment
ii. Preadministration assessment
iii. Dosage and administration
iv. Evaluating and promoting therapeutic effects
v. Minimizing adverse effects
vi. Minimizing adverse interactions
vii. Making PRN decisions
viii. Managing toxicity
f. Evaluating the therapeutic response with pt education
i. One of the most important aspects of therapy
ii. Must know the rationale for treatment and the nature and time
course of the intended response
iii. Cannot effectively evaluate a drug with multiple applications if the
intended use is not known
iv. Pt adherence
1. Compliance or concordance
2. Extent to which pt behavior coincides with medical advice
v. Implementing nondrug measures
1. Biofeedback, emotional support, smoking cessation, sodium
restriction with someone with HTN
g. Application of Pharmacology in PT education
i. Drug name and therapeutic category
ii. Dosage
iii. Dosing schedule
iv. Route and technique of administration
v. Expected therapeutic response and when it should develop
vi. Non drug measure to enhance therapeutic responses
h. Applying the nursing process in drug therapy
i. Preadministration assessment
ii. Analysis and nursing diagnosis
iii. Planning
iv. Implementation
v. Eval
i. Preadministration assessment
i. Collection of baseline data to evaluate the therapeutic effect of the
drug
ii. Collection of the baseline data to evaluate adverse effects
iii. Identify high risk patients
iv. Assessment of pt self care
j. Analysis and Nursing diagnosis
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