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BCHM 270 Midterm Test Quizzes Solved 100% Correct |Verified Solutions
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BCHM 270 Midterm Test QuizzesSolved 100% Correct |Verified
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Which of the following are true for amino acids that have nonpolar side chains?
a) They do not bind or release protons
b) They do not promote hydrophobic interactions
c) They can participate in ionic bonds
d) They can participate in hydrogen bonds
e) They tend to cluster on the surface of proteins. - Answer a)
pH - Answer -log[H+]
Prion protein - Answer Is the causative agent of mad cow disease.
Is present in normal mammalian brains on the surface of neurons.
Undergoes an exponential increase in the infectious form during disease.
Which of the following correctly describes a peptide bond?
a) The bond is uncharged and nonpolar
b) There is free rotation around the bond.
c) The bond is generally in the cis conformation.
d) The bond has a typical single bond character.
e) The bond is unstable at 110oC in the presence of a strong acid or base. - Answer e)
Which of the following is an example of a motif?
, a) The 3-D fold of myoglobin.
b) The tetrameric structure of hemoglobin.
c) The Gly-X-Y sequence of collagen
d) A beta barrel.
e) An beta-sheet - Answer d)
A mutation in hemoglobin has been discovered that abolishes the ability for the protein
to undergo the conformational change from the tense state to the relaxed state.
What effect will this have on oxygen binding of hemoglobin?
a) The mutant will have an increased affinity for oxygen.
b) The mutant will have a decreased affinity for oxygen.
c) There will be an increase in the sigmoidal nature of the binding curve.
d) The mutant will be less likely to release oxygen in the tissues.
e) None of the above. - Answer b)
Collagen - Answer Contains a high proportion of hydroxylated proline residues.
A fibrous protein.
The most abundant protein in the body.
Triple helix structure.
The structure is stabilized by hydrogen bonds between helices.
ATP - Answer Synthesis occurs in the mitochondrion.
Synthesis involves electrical and pH gradients.
Enzymes - Answer Lower the free energy of activation of a chemical reaction.
Do not change the free energies of the substrate(s) and product(s).
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