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PHCY 631: Flu Questions with Correct Answers
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PHCY 631: Flu Questions with Correct Answers
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PHCY 631: Flu Questions with Correct AnswersSeasonal influenza epidemics are the result of viral _____ ____, which
is why the influenza vaccine is changed on a yearly basis. This usually
consists of modifications/acquisition of new forms of _____ and/or
_____ Correct Answer-antigenic shift
hemagglutinin, neuraminidase
The primary route of influenza transmission is ____-___-_____ via
_____ of ___ ___ Correct Answer-person-to-person
inhalation
respiratory droplets
Give 6 common signs/symptoms of the flu Correct Answer-fever (abrupt
onset), muscle pain, headache, malaise, nonproductive cough, sore
throat, rhinitis
Symptoms of the flu usually resolve within _____ ____(s) of
presentation Correct Answer-1 week (3-7 days, cough and malaise can
last for more than 2 weeks)
TRUE or FALSE: The primary mechanism of influenza prevention in
the US is obsessive hand washing with alcohol-based hand sanitizer
Correct Answer-FALSE (~vaccination~ yo)
Both types of flu vaccine, both ______ and ___-____, contain what
subtypes of the flu? Correct Answer-inactivated
, live-attenuated
influenza A H1N1, Influenza A H3N2, influenza B
The antigens present in (most of) the flu vaccines are cultured/grown in
what type of medium? Correct Answer-hens' eggs
TRUE or FALSE: Antiviral drugs for prophylaxis of the flu should be
considered first-line monotherapy for the flu and generally replace the
vaccine Correct Answer-FALSE (Vax is first line)
The most effective time period for utilization of antiviral drugs during
flu infection is during the first ____ _____s of symptom onset Correct
Answer-48 hours
Give the 3 neuraminidase inhibitors that have activity against both
Influenza A and Influenza B viruses Correct Answer-oseltamavir,
zanamivir, peramivir
TRUE of FALSE: Adamantane antivirals have activity against Influenza
A, but not Influenza B. Also, there has been an increase in Influenza A
resistance to adamantanes. Therefore, they are not acceptable therapies
for influenza infection Correct Answer-TRUE
Nearly _________ individuals die of the flu each year in the US Correct
Answer-50000 (yup, you read that right. Nearly 650,000 deaths in the
world per year, 25-30 million cases in the US each year. Nearly $10
billion dollar annual healthcare expenditure on the flu)
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