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PHCY 631 - Pregnancy and Lactation Questions with Correct Answers
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PHCY 631 - Pregnancy and Lactation Questions with Correct Answers
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PHCY 631 - Pregnancy and Lactation Questions withCorrect Answers
Physiologic changes in pregnancy begin in the _____ trimester and peak
during the _____ trimester Correct Answer-1st, 2nd
During pregnancy, maternal plasma volume, cardiac output, and
glomerular filtration do what? What are the implications of this? Correct
Answer-Increase by 30-50% or higher
Potentially lowers concentration of renally-cleared drugs
During pregnancy, what happens to plasma albumin concentrations?
What is the implication of this? Correct Answer-Albumin concentrations
decrease
Higher Vd in protein-bound drugs
During pregnancy, which the activity of which P450 enzymes are
increased? Correct Answer-3A4
2C9
2D6
, During pregnancy, the activity of which P450 enzyme is decreased?
Correct Answer-1A2
During pregnancy, what happens to gastric acidity? Correct Answer-
Increases
During pregnancy, what physiologic change may alter the absorption of
drugs? Correct Answer-Nausea/vomiting, delayed gastric emptying
What supplements and vaccines are recommended during pregnancy?
Correct Answer-Folic acid 0.4-0.9mg daily recommended throughout
reproductive years to reduce risk of neural tube defects in offspring
Higher folate doses required in women who have previously delivered a
child with neural tube defects, or who are taking valproic acid
Inactivated flu vaccine (injection)
Tdap vaccine
What treatment for diabetes is preferred in pregnant women? Correct
Answer-Insulin
What is the most teratogenic epileptic drug? Correct Answer-Valproate
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