Pharmacy Foundations - Part I (NAPLEX
Book 2024)
Common Enzyme Inhibitors
G:
P:
A:
C:
M:
A:
N:
Grapefruit Juice
Protease Inhibitors
Azole Antifungals
Cyclosporine, Cobicistat, Cimetidine
Macrolide Antibiotics
Amiodarone, Dronedarone
Non-DHP CCB's (Diltiazem, Verapamil)
Common Enzyme Inducers
P:
S:
,P:
O:
R:
C:
S:
Phenytoin
Smoking
Phenobarbital
Oxcarbazepine
Rifampin
Carbamazepine
St. John's Wort
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Which of the following self-administered, injectable medications do NOT require refrigeration?
A. Lovenox
,B. golimumab
C. Tymlos
D. Enbrel
Correct Answer: A. Lovenox
Lovenox (Enoxaparin) is the only drug present that does not require refrigeration. Golimumab
(Simponi), Abaloparatide (Tymlos), Etanercept (Enbrel) all require refrigeration.
Injectable Medications that DO NOT Require Refrigeration
(1)
(2)
(3)
(4)
(5)
Enoxaparin (Lovenox)
Fondaparinux (Arixtra)
Methotrexate (Otrexup, others)
Sumatriptan (Imitrex, Zembrace, SymTouch)
Phenytoin (Dilantin)
Ear Drop Counseling
- Adults: Pull the ear ____________ and back
- Children < 3 yrs: Pull the ear __________ and back
up
, down
Vesicants
Drugs that are vesicants include: (9)
Vasopressors (Dopamine, Norepinephrine)
Anthracyclines (Doxorubicin)
Vinca Alkaloids (Vincristine, Vinblastine)
Digoxin
Foscarnet
Nafcillin
Mannitol
Mitomycin
Promethazine
Drugs with Leaching/Adsorption/Absorption Issues with PVC Containers
Leach Absorbs To Take In Nutrients
Lorazepam
Amiodarone
Tacrolimus
Taxanes (e.g. Paclitaxel)
Insulin
Nitroglycerin
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