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pharm exam 1 Galen questions with answers.
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pharm exam 1 Galen questions withanswers.
When the drug is in bloodstream after administration, is disintegrated out of stomach this is called?
A. metabolism
B. absorption
C. excretion
D. distribution ANS - B
The movement of a drug from circulatory system to body tissues is called what?
A. distribution
B. metabolism
C. excretion
D. absorption ANS - A
This occurs when a drug is altered in chemical structure, most are done in the liver.
A. excretion
B. distribution
C. absorption
D. metabolism (biotransformation) ANS - D
Elimination of drug from body through the following: kidneys, liver, feces, lungs, saliva, sweat, breast
milk.
A. excretion
B. distribution
C. metabolism
D. absorption ANS - A
100% of a drug is used when it is given by which route?
,A. intramuscular (IM)
B. intravenously (IV)
C. subcutaneously (subq)
D. orally (PO) ANS - B
1st pass effect goes from the ____ to the ____.
Only ____ % of med is going to make it through bloodstream due to this process. ANS - -stomach, liver
-30%
What are the two routes that can skip the 1st pass effect?
A. IM, sublingual
B. IV, sublingual
C. IM, subq
D. IV, subq ANS - B
When drug comes out of the first pass effect, it can go into the blood & be used in some way, the % of
administered drug available for activity is called?
A. peak
B. onset
C. trough
D. bioavailable ANS - D
What in the blood have receptor sites that will grab onto, hold onto med and decreased therapeutic
effect on drug?
A. carbs
B. electrolytes
C. proteins
, D. cells ANS - C
What is it called when the drug causes the effect & do not get taken up by proteins in blood?
A. free drug
B. extended release drug
C. protein binding drug ANS - A
When you take TWO high protein binding drugs the effect of the med is going to be _____ effect on the
body.
They are going to compete with one another for ____ sites which makes them become ____ ANS -
higher,
protein, free drugs
When a med has a ____ half life you may only need to take that med a couple times a week.
When a med has a ____ half life, it may need to be taken more often because when it ____ it becomes
____ therapeutic ANS - long,
short, decreases, less
When a drug becomes therapeutic this is called?
A. onset
B. peak
C. duration of action
The length of time a drug exerts a therapeutic effect is called?
A. duration of action
B. peak
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