Study Tip Gal Naplex
Daily Patches - ANS Daytrana (QAM 2h before school)
Nicoderm
Exelon
Neupro
Emsam
Androderm (nightly)
Daily Patches
(Special Instructions) - ANS Lidoderm (1-3 on for 12 h - 12 h off)
Nitroglycerin (on for 12-14 h - 10-12 h off)
Twice Daily Patches - ANS Flector
Twice Weekly Patches - ANS Alora, Vivelle-Dot
Oxytrol
Weekly Patches - ANS Butrans
Catapres-TTS
Climara, Menostar
ClimaraPro
Xulane (qwk for 3 wks - 1 wk off)
Other Patch Durations - ANS Duragesic (q72h or q48h)
Transderm Scop (q72h)
National Patient Safety Goals - ANS 2 patient identifiers (name, DOB, MRN)
Report critical test results
Label all medications
Anticoagulant therapy safety measures
Med information (med rec + D/C counseling)
Prevent HC-associated infections
CDC hand hygiene
,Penicillin Allergy AND Syphilis in Pregnancy or HIV - ANS Must test, and if positive, desensitize
PCN is the only acceptable treatment
Penicillin Allergy and AOM - ANS May use 2nd or 3rd gen cephalosporin
Cefdinir, Cefpodoxime, Ceftriaxone, Cefuroxime
Testing HLA-B*5701 - ANS Abacavir
If (+) --> risk of fatal hypersensitivity
(Test ALL patients prior)
Testing HLA-B*5801 - ANS Allopurinol
If (+) --> risk of SJS
(Consider testing in Korean + renal impairment, Han, or Thai)
Testing HLA-B*1502 - ANS Carbamazepine, Oxcarbazepine, Phenytoin
If (+) --> risk of SJS/TEN
(Test all Asian pts prior to Carbamazepine)
Testing CYP2C19 - ANS Clopidogrel
If *2 or *3 --> Poor metabolizers
(consider alt tx)
Testing CYP2D6 - ANS Codeine
Ultra-rapid --> risk of OD
Testing CYP2C9 + VKORC1 - ANS Warfarin
If CYP*2 or *3 or VKOR G>A --> increased bleeding risk
(start with lower dose)
Testing HER2 - ANS Trastuzumab
HER2 (-) --> drug not effective
Testing KRAS - ANS Cetuximab
If KRAS (+) --> Do not use
,Testing TPMT - ANS Azathioprine
TPMT activity low/absent --> risk of myelosuppression
(Use lower dose or consider alt tx)
Testing DPD - ANS Capecitabine, Fluorouracil
If DPD deficient --> risk of toxicity
(Do not use)
Common Symptomatic Treatment in Toxic OD - ANS Agitation - Sedatives (BZDs)
Bradycardia - Atropine, inotropes
Seizure - BZDs
Hypertension - IV vasodilator
Hypoglycemia - Dextrose
Hypotension - IVF, vasopressors
QRS widening - Sodium bicarb
Sedation - Intubation
Oral NAC Dosing - ANS 140 mg/kg x 1
70 mg/kg q4h x 17
(Repeat dose if emesis w/i 1 h of dose)
Acetadote Dosing - ANS 150 mg/kg over 60 min
50 mg/kg over 4 h
100 mg/kg over 16 h
Drugs that use GFR for Dosing - ANS Metformin
SGLT2 Inhibitors
Cockroft-Gault Weights - ANS <IBW --> TBW
Normal weight --> IBW
OW/Obese --> AdBW
ACEI/ARBs for Albuminuria - ANS WHO - All pts w/ albuminuria
WHY - Prevent KD progression
HOW - Inhibit RAAS --> efferent arteriole dilation
WHAT - Dec. pressure in glomerulus, dec. albuminuria, CV protection
Hyperkalemia Tx - ANS CA BIG K Drop
, Stabilize - Ca gluconate
Move it - Albuterol, Bicarb, Insulin, Glucose
Remove it - Kayexalate, Furosemide, Patiromer, Dialysis
Hepatitis A - ANS Acute
Fecal-Oral
Vaccine
Tx - Supportive
Hepatitis B - ANS Acute + Chronic
Blood, body fluid
Vaccine
Tx - PEG-INF or NRTI (tenofovir, entecavir)
Hepatitis C - ANS Acute + Chronic
Blood, body fluid
NO vaccine
Protease Inhibitors and Food - ANS PIG (Protease Inhibitors + Grub)
TAKE WITH FOOD
(except elbasvir/grazoprevir and fosamprenavir PO susp)
Acid Suppressive Therapy should be avoided with these HCV drugs: - ANS Harvoni
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