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NAPLEX - Compounding III Exam Questions and Answers 2024/2025( A+ GRADED 100% VERIFIED).
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NAPLEX - Compounding III Exam Questions and Answers 2024/2025( A+ GRADED 100% VERIFIED).
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NAPLEX - Compounding IIImaster formula sheet - ANS recipe followed to compound a preparation
what you SHOULD do
compounding log/record - ANS log book of all products made at the pharmacy
what you DID
where is it preferred to compound non-sterile HD drugs? - ANS in a containment primary
engineering control (C-PEC)
minimum PPE for compounding non-sterile non-HD compounds? - ANS clean lab coat
gloves
BUDs for repackaged drugs should be: - ANS the manufacturer's expiration date from the
original container or 1 year from the repackaging date (whichever comes 1st)
comminution - ANS reduce particle size by grinding, crushing, milling, vibrating (or other
processes - manual or mechanical)
powders will be finely ground into particles ranging in size from: - ANS 0.1-1 microns
sieves/sifters are used after the powder has been ground in order to... - ANS ensure that the
particle size is uniform
the sieve number is based on the... - ANS # of holes per inch
3 types of comminution - ANS levigation (and spatulation)
trituration
pulverization by intervention
trituration - ANS grinding into a fine powder
(can also triturate an emulsion by shaking it)
levigation - ANS same thing as trituration but with a levigating agent
--this will turn the solid into a uniform paste
, spatulation - ANS similar to levigation, but performed on an ointment slab with a spatula
(instead of a mortal/pestle)
pulverization by intervention - ANS used for crystalline powders that will not crush easily
--the crystals are dissolved with an intervening solvent and mixed until the solvent evaporates
geometric dilution - ANS mixing ingredients to ensure that they are evenly distributed in a
diluent or delivery vehicle
a small amount of drug powder will be mixed into an equal amount of diluent; this is repeated
until all ingredients are mixed together
when using multiple ingredients, begin with the ingredient that has the smallest quantity
solution - ANS solute dissolved in a solvent
homogenous
if the solute concentration is too high in a solution, this can lead to unwanted ___ - ANS
precipitation
types of solutions - ANS syrups
elixirs
tinctures
spirits
syrups - ANS oral solutions with sucrose, other sugars, or artificial sugars
elixirs - ANS sweet hydro alcoholic solutions used for drugs that would be insoluble in a purely
aqueous formulation
hydro alcohol = alcohol + water
tinctures - ANS plant or animal extracts dissolved in alcohol or hydro alcohol
spirits - ANS alcohols or hydro alcohols of volatile aromatic compounds like camphor
volatile - ANS the compound vaporizes easily (evaporates)
suspension - ANS solid dispersed in a liquid
--two-phase heterogeneous mixture
what type of surfactant is used to incorporate an insoluble drug into a liquid ---> suspension -
ANS levigating/wetting agent
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