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NAPLEX MOA EXAM QUESTIONS AND ANSWERS 2024/2025( A+ GRADED 100% VERIFIED).
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NAPLEX MOA EXAM QUESTIONS AND ANSWERS 2024/2025( A+ GRADED 100% VERIFIED).
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NAPLEX MOAadapalene - ANS topical retinoid for acne
brimonidine ophth (Alphagan) - ANS adrenergic alpha-2 agonist for glaucoma (reduce aqueous
humor production and increase aqueous outflow)
phenazopyridine (pyridium) - ANS Urinary analgesic to treat dysuria (pain or burning with
urination) during UTI
testosterone topical (Androgel) - ANS testosterone replacement for hypogonadism
gatifloxacin (zymar) - ANS quinolone antibiotic (inhibit bacterial DNA topo IV and DNA gyrase
which prevents supercoiling of DNA and promotes breakage of ds DNA)
moxifloxacin ophthalmic (vigamox) - ANS quinolone antibiotic (inhibit bacterial DNA topo IV and
DNA gyrase which prevents supercoiling of DNA and promotes breakage of ds DNA)
clindamycin - ANS lincosamide antibiotic (binds to 50S subunit of the bacterial ribosome
inhibiting protein synthesis)
mupirocin topical - ANS Topical Antibiotic for eradication and minor wounds
carbamazepine - ANS Narrow-spectrum antiepileptic/Na channel blocker (decreases neurons
firing rate)
Used in epilepsy
Used as pain mgmt adjuvant (neuropathic)
lacosamide (vimpat) - ANS Narrow-spectrum antiepileptic (stabilizes hyperexcitable neuronal
membranes and inhibits repetitive neuronal firing by enhancing the slow inactivation of Na
channels)
lamotrigine - ANS Broad-spectrum antiepileptic/Na channel blocker (decreases neurons firing
rate)
Used for focalized and generalized seizures
Used in bipolar depression
levetiracetam - ANS Broad-spectrum antiepileptic (Increases GABA and is also a Ca channel
blocker = slows down or stops transmission of the electrical signal)
Used for focalized and generalized seizures
,oxcarbazepine (trileptal) - ANS Narrow-spectrum antiepileptic/Na channel blocker (decreases
neurons firing rate)/Ca channel blocker (slows down or stops transmission of the electrical
signal)
topiramate - ANS Broad-spectrum antiepileptic/Na channel blocker (decreases neurons firing
rate)
Used for focalized and generalized seizures
Antimigraine ppx agent
divalproex (depakote) - ANS Antiepileptic (increases GABA)
Antimigraine ppx agent
phenobarbital - ANS Narrow-spectrum antiepileptic/barbiturate (enhances GABA effect)
phenytoin oral/injection (dilantin) - ANS Narrow-spectrum antiepileptic/Na channel blocker
(decreases neurons firing rate)
pregabalin oral - ANS Miscellaneous antiepileptic
Not really used in epilepsy
Used as pain mgmt adjuvant (neuropathic)
Also used for anxiety
gabapentin (neurontin) - ANS Miscellaneous antiepileptic/GABA analog (However, it does not
bind to GABA-A or GABA-B receptors, & does not appear to influence synthesis or uptake of
GABA. High affinity gabapentin binding sites in the brain correspond to the presence of
voltage-gated Ca channels specifically possessing the alpha-2-delta-1 subunit. This channel is
located presynaptically, and may modulate the release of excitatory NTs which participate in
epileptogenesis & nociception)
Used in epilepsy
Used as pain mgmt adjuvant (neuropathic)
diphenoxylate/atropine - ANS Antidiarrheal agents (diphenoxylate is an antimotility agent that
slows intestinal motility prolong water reabsorption in the gut. Atropine is an anticholinergic
agent)
Used for diarrhea and IBS-D
metoclopramide (reglan) - ANS Antiemetic agent/DA receptor antagonist (blocks DA receptors
int he CNS including the CTZ. Also enhances response to ACh in the upper GI tract, causing
enhanced motility, accelerated gastric emptying and increase LES tone which decreases GERD
sx)
Used in CINV
Also used in GERD + gastroparesis
,nystatin topical - ANS miscellaneous systemic nonabsorbed/Partially Absorbed antifungal agent
(Binds to sterols in fungal cell membrane, changing the cell wall permeability allowing for
leakage of cellular contents)
clotrimazole/betamethasone topical - ANS antifungal agent for fungal skin infections (athletes
foot, jock itch, ringworm, candida)
colchicine - ANS Antigout Agent (disrupts cytoskeletal functions by inhibiting β-tubulin
polymerization into microtubules, preventing activation, degranulation, and migration of
neutrophils associated with mediating some gout symptoms)
hydrocortisone topical (proctocort, cortaid, cortizone) - ANS for rectal or skin conditions
proctocort (rectal), cortaid (rectal), cortizone (skin)
anastrozole (arimidex) - ANS Aromatase inhibitor (decreases production of estrogen and
testosterone)
Used in breast cancer
benzonatate - ANS Cough suppressant (for nonproductive cough) for cough/cold (suppresses
cough by anesthetic action on the respiratory stretch receptors)
hydrocodone/chlorpheniramine - ANS mu-opioid receptor agonist/1st generation antihistamine
Used for temporary relief of cough and upper respiratory tract symptoms associated with allergy
or the common cold
alendronate oral (fosamax) - ANS bisphosphonate (inhibit osteoclast activity and bone
resorption)
Used for osteoporosis
ibandronate oral/injection (boniva) - ANS bisphosphonate (inhibit osteoclast activity and bone
resorption)
Used for osteoporosis
risedronate oral (actonel) - ANS bisphosphonate (inhibit osteoclast activity and bone resorption)
Used for osteoporosis
zoledronic acid injection (reclast) - ANS bisphosphonate (inhibit osteoclast activity and bone
resorption)
Used for osteoporosis
tacrolimus oral/injection (prograf) - ANS calcineurin inhibitor (suppresses cellular immunity by
inhibiting T-lymphocyte activation)
Used for maintenance immunosuppression in transplant
, cyclosporine ophthalmic - ANS calcineurin inhibitor (suppresses cellular immunity by inhibiting
T-lymphocyte activation)
Used for chronic drye eye disease and Sjogren's syndrome
ethinyl estradiol/desogestrel - ANS COC
ethinyl estradiol/drospirenone - ANS COC
medroxyprogesterone acetate oral (provera) - ANS Progesterone replacement used for
menopause
ethinyl estradiol/etonogestrel (nuvaring) - ANS combined contraceptive ring
ethinyl estradiol/norethindrone - ANS COC
ethinyl estradiol/norgestimate - ANS COC
loteprednol (lotemax) - ANS Ophthalmic corticosteroid
triamcinolone topical/injection (kenalog) - ANS systemic steroid used for autoimmune disorders
conjugated equine estrogen vaginal cream/vaginal tabs/injection (premarin) - ANS estrogen
replacement for menopause
17-beta-estradiol oral (estrace) - ANS estrogen replacement for menopause
estradiol transdermal patch (vivelle-DOT, Climara, Alora) - ANS estrogen replacement for
menopause
micronized progesterone oral (prometrium) - ANS progesterone replacement for menopause
bimatoprost for glaucoma - ANS PG analog for glaucoma (increase aqueous flow)
latanoprost - ANS PG analog for glaucoma (increase aqueous flow)
travoprost - ANS PG analog for glaucoma (increase aqueous flow)
raloxifene - ANS SERM (estrogen agonist/antagonist that decreases bone resorption)
Used for osteoporosis and breast cancer
cyanocobalamin - ANS Vitamin B12 supplement for anemia
allopurinol (zyloprim, aloprim) - ANS Antigout ppx agent/xanthine oxidase inhibitor (decreases
uric acid production)
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