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2024 251 PHARMACOLOGY TEST 1 EXAM WITH CORRECT ANSWERS
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2024 251 PHARMACOLOGY TEST 1 EXAM WITH CORRECT ANSWERS
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2024 251 PHARMACOLOGY TEST 1EXAM WITH CORRECT ANSWERS
Drug Names include - CORRECT-ANSWERS1. Chemical Name
2. Describe the chemical composition and molecular structure
3. Generic name - nonproprietary name
4. Trade name - Owned by the producing company.
Pharmacology - CORRECT-ANSWERSStudy of chemicals that alter the
function of living organisms.
Drugs can be used to: - CORRECT-ANSWERS1. Prevent disease
2. Diagnose Disease
3. Cure disease
4. Treat symptoms of disease
Classification of drugs based on similarities of properties - CORRECT-
ANSWERS1. Structure - e.g. beta blockers
2. Use - e.g. antibiotics
Interferon description (6) - CORRECT-ANSWERS1. Biological response
modifiers
2. Bind to specific cell surface receptors
3. Alter intra-cellular activities
4. Boost the immune system and prevent virus from entering cells
5. Anti viral and anti neoplastic in effect.
6. Inhibits viral replication by reprogramming virus.
Interferon use - CORRECT-ANSWERShairy cell leukemia, Kaposi's sarcoma,
chronic hepatitis
Interferon adverse effects - CORRECT-ANSWERSFlu like symptoms,
depression, suicide
Interferon - how it works (3) - CORRECT-ANSWERS1. inhibits viral replication
by reprogramming virus
2. prevents rapid growth of malignant cells
3. Increases cyto activity of NK cells.
Roferon - A or Intron- A generic name - CORRECT-ANSWERSInterferon Alfa 2a
or 2b trade names
,Interferon Alfa 2a or 2b (Roferon-A or intron-A) - CORRECT-
ANSWERSInterferon
Monoclonal antibodies description - CORRECT-ANSWERS1. Specifically target
cancer cells and have minimal effect on healthy cells.
2. Compliance is an issue because taken at home as a pill.
Monoclonal antibodies uses - CORRECT-ANSWERS1. Rheumatoid Arthritis,
Crohn's disease, Cancer, MS, and organ transplantation
2. Neutralizes activity of tumor necrosis factor alpha
Monoclonal antibodies Adverse effects - CORRECT-ANSWERS1. Fewer
adverse effects than traditional anti neoplastic meds.
2. Flu like symptoms
3. Varies with drug.
generic name for Remicade - CORRECT-ANSWERSInfliximab
Infliximab (Remicade) - CORRECT-ANSWERS1. Monoclonal Antibody
Infliximab (Remicade) uses - CORRECT-ANSWERS1. For arthritis
2. Tumor necrosis factor - A cytokine - something that prevents inflammation
from happening.
Interleukins description - CORRECT-ANSWERS1. Activates cellular immunity
2. Inhibits tumor growth
3. Prevents rapid growth of malignant cells
Proleukin generic name - CORRECT-ANSWERSAldesleukin trade name
Aldesleukin (Proleukin) - CORRECT-ANSWERSInterleukin drug
Interleukin uses - CORRECT-ANSWERS1. Renal cancer
2. Melanoma
3. HIV
4. Kaposi Sarcoma
Interleukin adverse affects - CORRECT-ANSWERSCapillary leak syndrome
causing caps to lose ability to retain colloids, proteins and albumin which
causes massive fluid retention.
Anti-rheumatic Arthritis drugs (2 examples) - CORRECT-ANSWERS1.
Etanercept (Enbrel)
2. Abatacept (Orencia)
, Enbrel generic name - CORRECT-ANSWERSEtanercept trade name
Orencia generic name - CORRECT-ANSWERSAbatacept trade name
Etanercept (Enbrel) - CORRECT-ANSWERS1. Anti-rheumatic arthritis drug.
2. Also juvenile RA
3. Psoriasis
4. Screen for latex allergy
5. Contraindicated if active infections are present
Abatacept (Orencia) - CORRECT-ANSWERS1. Anti-rheumatic arthritis drug.
2. For RA
Abatacept (Orencia) problems - CORRECT-ANSWERSAnti rheumatic arthritis
1. History of recurrent infections or COPD
2. Up to date immunizations before therapy
3. May increase risk of infections
4. May decrease response to vaccines
5. No use if active infection present.
6. Can reactivate TB or hepatitis infections from the past.
Immunosuppressant description - CORRECT-ANSWERS1. Interfere with
production or function of immune cells
2. Inhibits T-lymphocytes
3. suppresses the immune system
Immunosuppressant use - CORRECT-ANSWERSprevention of organ rejection,
arthritis
Immunosuppressant adverse - CORRECT-ANSWERSTremors, HA, oral
candida, seizures, HTN, nephrotoxicity, opportunistic infections, many drug
interactions
generic name for Sandimmune or Neoral - CORRECT-ANSWERSCyclosporin (2
trade names)
Cyclosporin ( Sandimmune or Neoral) - CORRECT-
ANSWERSImmunosuppressant drug
Immunosuppressant nursing implications (11) - CORRECT-ANSWERS1. Need
contraceptive during treatment and unto 12 weeks after.
2. Take drug at same time every day
3. Take with meals
4. Use same solution
5. Follow instructions to mix.
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