Nitroglycerin can be used in _____ to _____ ✅heart failure patient;
Lower BP
, Normal effects of nitroglycerin ✅3 h's
3 H's ✅headache
Hypotension
Hot flushing
Do not use nitroglycerin in conjunction with... ✅viagra
(ED drugs that end in "afil")
Why? ✅can cause extremely low BP that can be deadly
What should be monitored with nitroglycerin use? ✅BP
Nitroglycerin should be held for... ✅SBP <100
Important teaching for patients on nitroglycerin ✅change positions slowly
Topical patch nitroglycerin teaching ✅remove patch for 8 hours at night to prevent
tolerance
Sublingual nitroglycerin teaching ✅store in original container
Exposure to air/moisture can inactivate the drug
Nitroglycerin has potent _____ effects on _____ ✅dilating;
Coronary arteries
Why is nitroglycerin given via other routes as opposed to orally? ✅large first-pass
effect
Heart failure drugs ✅cardiac glycosides
Catecholamines (adrenergic agonists)
Cardiac glycoside drugs ✅digoxin
Digoxin MOA ✅increases myocardial contractility
(positive inotropic effect)
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