NURS8024 Pharm Exam 3 (Antimicrobial Part 1) –
Questions And Answers (Graded A+)
Gram-positive bacteria Right Ans - Stain violet purple
Gram-negative bacteria Right Ans - Stain pink
Aerobes Right Ans - require oxygen, most common cause of infection
Common gram positive aerobes Right Ans - MRSA(staphylococci),
Streptococci, Enterococcus, Vanc resistant enterococcus (VRE)
Common gram negative aerobes Right Ans - Moraxella catarrhalos,
gonorrhea, jarmo Philips influenzae (HIB)
Space bugs Right Ans - Hard to treat organisms
Serratia, pseeudomonas aeriginosa, acinetobacter helocobacter, citrobacter,
enterobacter
Anaerobes Right Ans - Thrive without bacteria
Release exotoxins
Local microbiota enter sterile tissue
common anerobes Right Ans - C-dif, fusobacterium, actinomyces
(abdominal infections), bacteroides fragilis
Atypical bacteria Right Ans - Legionella pneumophila, mycoplasma
pneumonia, chlamydia pneumoniae/trachomatis
Spirochetes Right Ans - Treponema pallidum
Borrelia burgdorferi
Narrow spectrum antibiotics Right Ans - Act on single or limited group of
microorganisms
Known pathogen
Ideal
, Extended spectrum antibiotics Right Ans - Efficacy against large numbers
of gram positive or gram negative organisms
Broad Spectrum (empiric therapy) Right Ans - Effective against broad
spectrum
Unknown pathogen, but possibly life threatening
Risk for superinfections
Superinfections Right Ans - Use of broad spectrum agents can disrupt the
normal flora causing growth of opportunistic organisms (PCN causing vag
yeast)
Empiric regimen Right Ans - Imitated before the offending organism
identified and sometimes prior to confirmation of infection
Definitive regimen Right Ans - Initiated when causative organism is known
Minimum inhibitory concentration (MIC) Right Ans - Estimate of the drug
sensitivity of pathogens for comparison with anticipated levels in blood or
tissues
Post-antibiotic effect (PAE) Right Ans - AB effect that persists after drug
concentration falls below the MIC
Susceptibility testing Right Ans - Laboratory methods to determine to the
sensitivity of the isolated pathogen to anti microbial drugs
Bacteriostatic antomicrobial Right Ans - Inhibits growth and replication of
bacteria
Limits spread of infection
Enables immune system to attack pathogen
Bacterialcidal antimicrobial Right Ans - Kills bacteria
Total number of viable organisms decreases
Concentration-dependent killing Right Ans - Increased rate of killing with
increased concentration
Usually offers a daily dose to achieve efficacy
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