Exam (elaborations)
Adv Pharm NURS8024 - Endocrine: Diabetes – Qs And As
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Adv Pharm NURS8024 - Endocrine: Diabetes – Qs And As
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Adv Pharm NURS8024 - Endocrine: Diabetes – Qs AndAs
Describe the mechanism for Type 1 DM? Right Ans - Pancreas attacks cells
that produce insulin - Body CANNOT make Insulin
Describe the mechanism for Type II DM? Right Ans - Body is resistant to
insulin. Body makes insulin but body does not respond to it
What is the goal A1C for DM Management? Right Ans - < 7 % - Decreases
microvascular complications
Metformin is considered the _____________ _______________ treatment for DM.
Right Ans - 1st Line
Describe the MOA for Metformin: Right Ans - Decreases Hepatic Glucose
Production
Please list the BBW for Metformin. Right Ans - Lactic Acidosis (Rare Renal
and Tissue Hypoxia)
What clinical consideration is important for patients on Metformin? Right
Ans - Impaired Renal Fx and Hold for 24 hrs post IV Dye Load
What is the MOA for Sulfonylureas to control Blood Sugar? Right Ans -
Increase in endogenous insulin secretion by binding to receptors on
prancreatic beta cells = Insulin production
Metformin and Sulfonylureas have the same efficacy for blood glucose control
which is? Right Ans - Fasting BG to 60 - 70 mg/dL and Decrease A1C 1 - 2
%
Name a unique SE to Sulfonylureas? Right Ans - Photosensitivity
What is the MOA for Thiazolidinedions (TZDs) Right Ans - Insulin
Resistance by Increase in Muscle and Fat sensitivity to insulin & SUPPRESSES
HEPATIC GLUCOSE Production
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