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NURB 3150 Anti-diabetics Exam With Complete Solution
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NURB 3150 Anti-diabetics ExamWith Complete Solution
Rapid-acting - Answer Lispro, Aspart, Glulisine
Short-acting - Answer Regular
Intermediate-acting - Answer NPH
long-acting - Answer Insulin glargine, insulin detemir
lispro, aspart, glulisine - Answer Onset:<15 min
Peak: 0.5-1 hr
Duration: 3-4 hr
regular insulin - Answer Onset: 0.5-1 hr
Peak: 2-3 hr
Duration: 5-7 hr
NPH insulin - Answer Onset: 1-2 hr
Peak: 4-12 hr
Duration: 18-24 hr
insulin glargine, detemir - Answer Onset: 1 hr
Peak: none
Duration: 10-24 hr
Insulin - Answer hormone produced by pancreas decreases blood glucose by
increasing transport of glucose and potassium into cells (for energy) promotes
conversion of glucose to glucagon
Insulin - Answer AE: Risk for hypoglycemia, Lipohypertrophy, Somogyi, Dawn
phenomenon
Somogyi effect - Answer Rebound HYPERglycemia in AM in response to
counterregulatory hormone release after episode of hypoglycemia in middle of the night
3 am BG is decreased. decrease the evening insulin to avoid nocturnal hypoglycemia
, Dawn phenomenon - Answer natural increase in early am BG and insulin requirements
due to increased glu production in liver after overnight fast-increased need for insulin at
dawn
Insulin - Answer Sulfonyreas, meglitinides, beta blockers and ETOH= Increase
hypoglycemia
Thiazide diuretics and glucocorticoids= Increased blood glucose, counteracts insulin
hypoglycemia - Answer tachycardia
palpitations
diaphoresis
shakiness
HA
tremors
weakness
lipohypertrophy - Answer rotate injection sites
Sulfonylureas - Answer An oral antidiabetic that increases insulin production from
pancreas (beta cells), decreases BS in pts with functioning pancreas
medicine accumulation - Answer Pts who have renal failure, hepatic dysfunction, or
heart failure can result in hypoglycemia when taking oral antidiabetics because of the
risk of _________ _______________
weight gain - Answer common side effect of sulfonylureas
alcohol - Answer When using _________ with Sulfonylureas cause disulfiram reactions
and hangover like symptoms:
-Intense N/V
-Flushing
-Palpitations
beta blockers - Answer mask SNS response to hypoglycemia
Sulfonylureas - Answer Glipizide
Glimepiride
Glyburide
*best taken 30 minutes prior to meal
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