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AHN 577 Infectious Disease Part 2 Test With Complete Solution
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AHN 577 Infectious Disease Part 2 Test With Complete Solution...
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AHN 577 Infectious Disease Part 2 TestWith Complete Solution
Latent TB prevention - ANSWER Isoniazid x 9 months
Latent TB with positive TB skin test or IGRA - ANSWER Rifampin daily x 4
months
Rifampin + Pyrazinamide combo use in latent TB - ANSWER Contraindicated
d/t risk for severe liver injury or death
Active TB treatment during intensive phase - ANSWER RIPE (Rifampin,
Isoniazid, Pyrazinimide, Ethambutol) x 8 weeks
Active TB treatment during continuation phase - ANSWER Isoniazid and
Rifampin x 18 weeks
TB patient infectious if.. - ANSWER - Coughing
- Cavity in lung
- Sputum smears positive for AFB
- TB disease of lungs, airway, or larynx present
- Positive culture
TB patient no longer infectious if.. - ANSWER - Symptoms improved AND
- 3 consecutive negative sputum smears AND
- Adhering to adequate treatment x 2 weeks
How do you test for HIV infection? - ANSWER -- ELISA - initial screening;
,99.9% sensitive
-- Western blot - > 99.99% sensitive and specific
Routine labs for treatment of HIV/AIDS - ANSWER -- CD4 count - best
indicator of immune fx; guides therapy
-- HIV RNA - amt of actively replicating viruses; best indicator for diagnosing
acute HIV infections; tells about disease progression
-- CBC - detect pancytopenia
-- CMP - assess renal/hepatic function
-- Pregnancy test - prior to ARTs
-- UA to detect early nephropathy
-- Hgb A1c to assess for glucose intolerance
Typical initial regimen for HIV - ANSWER 1 integrase inhibitor (or PI) + 2
NRTIs
NRTI examples - ANSWER Tenofovir, Emtricitabine, Abacavir, Lamivudine
Common s/e of NRTIs - ANSWER - Hepatitis
- Neutropenia
- AKI
- Anemia
- Rash
- Peripheral neuropathy
- GI upset
, NNRTI examples - ANSWER Efavirenz, Nevirapine
Common s/e of NNRTIs - ANSWER - Rash
- Peripheral neuropathy
- Depression
Protease inhibitor examples - ANSWER Darunavir, Cobistat
Common s/e of PIs - ANSWER - Hyperbilirubinemia
- Rash
- GI upset
Entry inhibitor examples - ANSWER Maraviroc, Enfuviritide
Common s/e of entry inhibitors - ANSWER - Cough
- Fever
- Rash
Integrase inhibitor examples - ANSWER Raltegravir, Elvitegravir
Common s/e of integrase inhibitors - ANSWER - Rash
- Headache
- GI upset
How often should CD4/viral loads be monitored? - ANSWER 1-2 months post
initiation/change, then every 3-4 months after
With compliance, viral loads should be undetectable within ____ weeks -
ANSWER 24
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