Exam (elaborations)
NURS 5315 ADV PATHO EXAM 2 SET 1 QUESTIONS AND ANSWERS
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NURS 5315 ADV PATHO EXAM 2 SET 1 QUESTIONS AND ANSWERS
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Name: Score:102 Multiple choice questions
Definition 1 of 102
Humoral Immune response
mature into plasma cells which produce antibodies
antibodies [f] is to neutralize bacterial toxins
Dendritic cells
Antigen presenting cells
Macrophages
B lymphocytes (B cells)
Definition 2 of 102
anti-inflammatory properties
gastric mucosa
Role/function in the inflammatory process: Leukotriene b4 (ltb4)
Role/function in the inflammatory process: cortisol
Role/function in the inflammatory process: bradykinin
Role/function in the inflammatory process: Histamine 2 (H2)
Definition 3 of 102
HIV infection when total CD4 count is = to or above 200 and has never had an OI
AIDS diagnosis when a person has an AIDS defining illness and/or have a CD4 count below
200.
Hiv pathogenesis
Candida
Streptococci
HIV versus AIDS
,Definition 4 of 102
The immune response is mediated by T-cells and is a slow process
organ transplanted
antigen-presenting cells present HLA to both CD4 and CD8 cells
T-cell proliferation produces Th1 & Th2
*Th1 secretes cytokines which activate cytotoxic T-cells IL2 receptors, then binds - complex is
able to cause allogenic cell lysis and further stimulates T-cell proliferation
*Th2 secrete cytokines which stimulate B-cell immunity, then produce antibodies and bind w/
allogenic cells which trigger inflammatory cascade and complement deposition and cell lysis
solid organ transplant rejection: clinical application/treatment
Steps in the arachidonic acid pathway
Function of arachidonic acid pathway
solid organ transplant rejection: pathophysiology
Definition 5 of 102
inhibit the action of phospholipase A2 thus preventing the formation of prostaglandins,
thromboxane A2 prostacyclin and leukotrienes
Glucocorticoids
Antihistamines
Corticosteroids
Aldosterone
Definition 6 of 102
derived from fatty acids in the plasma membrane
produced by neutrophils, monocytes, endothelial and platelets
cause endothelial cell retraction, increases vascular permeability, activates platelets, enhances
leukocyte adhesion to endothelial cell
Role/function in the inflammatory process: platelet-activating factor
Role/function in the inflammatory process: interferon gamma (ifn-γ)
Role/function in the inflammatory process: nitric oxide (no)
Role/function in the inflammatory process: transforming growth factor beta (tgf-β)
,Definition 7 of 102
E: chronic systemic disease characterized by autoimmune inflammatory changes in the
connective tissue throughout the body but primarily in the joints
P: IgM autoantibodies combine w/ IgG antibodies to form antigen-antibody complex
deposited in synovial membranes
membranes infiltrated w/ T-cells, plasma cells, macrophages leading to inflammatory process,
then tissue damage
* progressive disease - damage irreversible
CM: widespread symmetrical joint swelling, erythemic joints, anorexia, weakness
Allergic Response Type 1 Hypersensitivity:
Etiology, pathophysiology, clinical manifestations
rheumatoid arthritis (RA):
Etiology, pathophysiology, clinical manifestations
clinical manifestations of infectious disease
solid organ transplant rejection: pathophysiology
Definition 8 of 102
Protein molecules (self-antigens) on surface of cells not antigenic to self but antigenic to
others in transfusions or grafts
Exogenous Pyrogens
Communicability
Define antigen
Define Self-Antigens
Definition 9 of 102
contain granules that attack and kill virus-infected or cancerous cells
function of NK (natural killer) cells
b lymphocytes (b cells)
Organs of the immune system
antigen presenting cells
, Definition 10 of 102
a strain of enterococcus bacteria that cannot be controlled with antibiotics; it is spread
through direct and indirect contact
Both A And b
Pediculosis Capitis (head lice)
Vancomycin Resistant Enterococcus (VRE)
Mrsa (methicillin resistant s. aureus)
Definition 11 of 102
ability to cause disease
Pathogenicity
Virulence
Infectivity
Toxigenicity
Definition 12 of 102
Ability of pathogens to induce an immune response
Immunogenicity
Infectivity
Virulence
Pathogenicity
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