2 resources for drug shortages Correct Answers FDA drug
shortages website
ASHP drug shortage website
3 specific properties for successful transdermal and dermal
delivery Correct Answers <600 Da
low melting point
large drug dose
35 year old female living with HIV presents to the infectious
disease clinic with a two week history of white plaques in her
mouth and painful swallowing. She has a history of poor
adherence to antiretrovirals the doctor would like to prescribe
fluconazole 100 milligrams daily for esophageal Candidiasis and
asks you, the clinical pharmacist, if tablets are the only option.
You check the fluconazole monograph:
solution, IV: 100mg, 200mg, 400mg
suspension reconstituted, oral: 10mg/mL, 40mg/mL
tablet, oral: 50mg, 100mg, 150mg, 200mg
Your recommendation is
A. she will just have to deal with swallowing tablets
B. only alternative is IV solution so she will have to be admitted
to the hospital
C. the pharmacy can compound an extemporaneous suspension
D. prescribe 2.5 mL of the 40 mg/mL oral suspension daily to
equate 100 mg
E. prescribe 100 mL of the 10 mg/mL oral suspension daily to
equate 100 mg Correct Answers D
,4 advantages of liposomes for ocular delivery Correct Answers
enhanced bioavailability
controlled release
targeted delivery
improved efficacy
A 24 year old female is recovering in the intensive care unit
after a motor vehicle accident. She is mechanically ventilated
and recently had an enteral tube placed for enteral feedings. She
is prescribed multiple medications in the team asks you if any
can be administered via the enteral tube. This is / these are
general considerations regarding enteral tube administration of
medications:
A. compatibility of the medication with tube feedings
B. PH dependent dissolution of the medication
C. accuracy of medication dosing
D. all of the above Correct Answers D
A 65 year old male with a history of diabetes and hypertension
is in the neurology intensive care unit for observation following
a cerebral vascular incident. He was given tissue plasminogen
activator TPA alteplase upon presentation to the emergency
Department. He regained a significant amount of functioning but
is still experiencing dysphasia. The team asks you, the clinical
pharmacist, if his medications can be crushed and mixed with
applesauce for administration. The first stop on your literature
search is the do not crush list. The organization that maintains
this list is the:
A. Institute for safe medication practices
B. Food and Drug administration
C. United States pharmacopoeia
, D. American Heart Association Correct Answers A
accumulation of triglyceride particles at the top of an emulsion
Correct Answers creaming
an IV solution has a shelf life of 5 hours at room temp (25
degrees C). what is the shelf if stored int he fridge at 5 degrees
C? Correct Answers 5/3^((5-25)/10)
45 hours
an oral suspension has a shelf life of 48h at 5 degrees C. what is
the estimated shelf life at room temp (25 degrees C)? Use Q
value of 3 Correct Answers 48/3^((25-5)/10)
5.33 hours
are the following dosage forms considered single-unit or
multiple unit?
capsule
granule
pellet
tablet
mini-tablet Correct Answers single
multi
multi
single
multi
average skin (epidermis and dermis) thickness Correct Answers
2.1mm