Psychopharmacology, Fourth Edition By
Meyer: Chapter 1 Questions With
Correct Answers.
pharmacology - ANSWER- study of the actions of drugs and their effects on living
organisms
neuropharmacology - ANSWER- area of pharmacology specializing in drug-induced
changes to the function of cells in the nervous system
psychopharmacology - ANSWER- area of pharmacology specializing in drug-induced
changes in mood, thinking
neuropsychopharmacology - ANSWER- area of pharmacology focusing on chemical
substances that interact with the nervous system to alter behavior, emotions, and
cognition
drug action - ANSWER- specific molecular changes associated with a drug binding to a
particular target site or receptor
drug effects - ANSWER- alterations in physiological or psychological functions
associated with a specific drug
therapeutic effect - ANSWER- desired physical or behavioral change associated with a
particular drug
side effect - ANSWER- undesired physical or behavioral change associated with a
particular drug
specific drug effects - ANSWER- physical or behavioral changes associated with
biochemical interactions of a drug with the target site
nonspecific drug effects - ANSWER- physical or behavioral changes not associated with
the chemical activity of the drug-receptor interaction but with certain unique
characteristics of the individual such as present mood or expectations of drug effects
(based on certain unique characteristics of the individual)
bioavailability - ANSWER- concentration of drug present in the blood that is free to bind
to specific target sites
, pharmacokinetic - ANSWER- factors that contribute to bioavailability: the administration,
absorption, distribution, binding, inactivation, and excretion of a drug
enteral - ANSWER- drug administration by oral or rectal routes (GI tract)
parenteral - ANSWER- methods of drug administration that do not use the
gastrointestinal system, such as intravenous, inhalation, intramuscular, transdermal, etc
oral administration (PO) - ANSWER- method that involves administration of a drug
through the mouth.
first pass metabolism
safe and economical
absorption - ANSWER- movement of a drug from the site of administration to the
circulatory system
first pass metabolism - ANSWER- phenomenon in which the liver metabolizes some of
a drug before it can circulate through the body, particularly when the drug has been
taken orally
rectal administration - ANSWER- drug delivery method, such as suppository, used to
deliver drugs via the lower intestine.
may avoid first pass met, depending on placement
bioavailibility difficult to predict
intravenous (IV) - ANSWER- method that involves administration of a drug directly into
the bloodstream by means of a vein.
rapid and accurate
quick onset dangerous
intramuscular (IM) - ANSWER- method that involves administration of a drug into a
muscle
slower
more absorption over a period of time
oil or constrict blood vessels makes slower
intraperitoneal (IP) - ANSWER- injection technique that is the most common route of
administration for small laboratory animals. The drug is injected through the abdominal
wall into the peritoneal cavity - the space that surrounds the abdominal organs
most used in lab animals
subcutaneous (SC) - ANSWER- method that involves injection of a drug just below the
skin.
slow and steady but variable
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