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Leptin and Ghrelin with complete verified solutions 2025
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Leptin and Ghrelin with complete verified solutions 2025
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Leptin and Ghrelinwith complete verified
solutions 2025
anorexigenic - answer output, makes you skinny
appetite suppressant. leptin, 95% in adipose tissue, rest chief cells
in stomach
orexigenic - answer input, makes you big. ghrelin secreted by PD1
and G cells in GI
leptin - answer mostly beta adrenergic, correlated with BMI,
adipose tissue mass
stimulates sympathetic system to increase energy expenditure
increases ACTH and TSH
^feeding decreases energy expenditure
Insulin like leptin: Own receptor in same dark (ARC) nucleus
Ghrelin - answer activated by acylation by GOAT, doesnt influence
ARC nucleus--has its own pathway
levels correlate with feeding
stimulates feeding (hyperphagia) and decreases energy expenditure
inhibits insulin secretion
regulates hepatic glucose output
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