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Acetylsalicylic acid (aspirin) Questions and Answers
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Acetylsalicylic acid (aspirin) Questions and Answers Classification antipyretic, non-opioid analgesic, salicylate Primary use antiplatelet activity-primary prevention MI, stroke, treatment of acute MI, stroke, TIA to prevent occurrence Previous Play Next Rewind 10 seconds Mov...

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  • September 28, 2024
  • 3
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • acetylsalicylic acid aspirin questions and answe
  • classification antipyretic non opioid analgesic
  • primary use antiplatelet activity primary preventi

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Acetylsalicylic acid (aspirin) Questions
and Answers
Classification - answer antipyretic, non-opioid analgesic, salicylate

Primary use - answer antiplatelet activity-primary prevention MI, stroke, treatment of
acute MI, stroke, TIA to prevent occurrence

Other uses - answer - analgesic- mild to moderate pain (325-650 mg q 4h)
- antipyretic- adults only
- anti-inflammatory- osteoarthritis, rheumatoid arthritis, spinal condiitons, (higher doses)

What is aspirin least commonly used for? - answer inflammation, other NSAID's
create equal effect with lower dose

Action - answer - blocks transmission of pain impulses in nerve fibers, central and
peripheral
- block transmission of pain receptors on cells from chemical substances
- prevent hypothalamus from reaching pyrogens, lower body temp
- block prostaglandin from increasing pain and edema
- low dose used for (75-81 mg) antiplatelet activity

Duration of action - answer 6-8 hours for pain relief and anti inflammatory properties,
but antiplatelet activity lasts for the life of a platelet

Black box warning - answer children/adolescent with chicken pox, flu- like symptoms,
viral symptoms should use acetaminophen instead, could cause Reyes Syndrome

Pregnancy category - answer D

Use in patients with renal impairment - answer - nephrotoxic in high doses
- protein binding is reduced in patients with renal failure which means blood levels of
active drug are higher than they would be otherwise
- when renal blood flow is decreased synthesis of prostaglandins is increased and they
protect kidneys, with prostaglandins blocked, no protection

Adverse effects - answer - GI: nausea, dyspepsia, heartburn, epigastric discomfort,
GI blood loss, hemorrhage
- petechiae and bruising

Toxicity occurs at levels above? - answer 300 mcg/mL

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