ADVANCED PHARMACOLOGY FINAL EXAM REVIEW | 2024| QUESTIONS WITH COMPLETE SOLUTIONS |RATED A+
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Course
NUR 3145.
Institution
NUR 3145.
ADVANCED PHARMACOLOGY FINAL EXAM REVIEW | 2024| QUESTIONS WITH COMPLETE SOLUTIONS |RATED A+
Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin therapy? - To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone i...
ADVANCED PHARMACOLOGY FINAL EXAM REVIEW | 2024|
QUESTIONS WITH COMPLETE SOLUTIONS |RATED A+
Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin
therapy? - To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? - Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH level
with? - Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - Aldosterone
antagonist
Heparin exerts its therapeutic action by what? - Upregulating the activity of one of the
body's natural anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug is administered during an
anaphylactic reaction. - Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications? - Photo-therapy and topical
corticosteroids
What is the first choice of drug therapy for the majority of patients with uncomplicated
stage I hypertension? - Thiazide diuretics
What is the effect of cardiac glycosides? - Digitalis glycosides have a negative
chronotropic effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control medication? -
Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for available beta-
receptor sites? - Atenolol (Tenormin)
What type of action does nitrates have on the body? - Reduction in systemic venous
tone.
, What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients
with known coronary artery disease? - 100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - Depressing phase 4
depolarization and lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid
hormones and re-establish eumetabolic state in a patient with Graves' disease? - Anti-
thyroid drugs.
Which type of diuretic would be used for a stage I hypertension in a patient with renal
insufficiency? - Loop diuretic.
What drug should be considered as first-line therapy for a client with hypertension and
heart failure? - Enalapril (Vasotec)
Which drug is considered safe for hypertension treatment during pregnancy? -
Methyldopa (Aldomet)
What drug will reduce afterload because it is an alpha-adrenergic blocker? - Prazosin
(Minipress)
What is an expected effect of the use of a beta-adrenergic blocker to control angina? -
Reduced force of cardiac contraction.
What side effect should be monitored closely in the elderly when taking Metformin
(Glucophage) for type 2 diabetes? - Lactic acidosis.
What is the primary role of cytochrome p-450 in the liver? - Deactivate and detoxify
medications and other substances.
What is a component of Vitamin K-dependent clotting factors? - Prothrombin
How are IV morphine and nitroglycerin beneficial in acute heart failure? - Decrease
preload.
What is the purpose of administering a vasodilating drug to a patient in heart failure? -
Decrease afterload.
What are some contrindications for HMG-co A reductase inhibitors (statins)? - They
cause myopathies, especially at higher doses or in combination with certain drugs. They
should never be used in patients taking Warfarin (Coumadin).
Which drug can reduce serum LDL the most in patients with hyperlipidemia? -
Lovastatin (Mevacor)
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