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PSIO 303 Exam 3 Questions With Complete Solutions
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PSIO 303 Exam 3 Questions With Complete Solutions
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PSIO 303 Exam 3 Questions With Complete SolutionsA chemical messenger secreted by one cell and acting on the
same cell in the same tissue is an example of paracrine
communication. Correct Answer False
A person with the Metabolic Syndrome will very likely end up
with a reduced level of insulin secretion by beta cells. This will
almost certainly manifest in many symptoms. Which of the
following is NOT a symptom that would arise as a result?
A Less inhibition of glucagon secretion from alpha-cells in the
pancreas.
B. An increase in gluconeogenesis
C. An increase in glycogenolysis
D. A decrease in pancreatic alpha-cell secretion of somatostatin.
Correct Answer D.
A person with the Metabolic Syndrome will very likely end up
with a reduced level of insulin secretion by beta-cells. This will
almost certainly lead to: Correct Answer less inhibition of
glucagon secretion from alpha-cells in the pancreas
About 30 minutes after consuming a very heavy traditional
Thanksgiving dinner, one's glucagon:insulin ratio will be:
Correct Answer supressed
ACh receptors are ligand-gated ion channels that permit the
movement of what ion when ACh binds? Correct Answer Na+
,Activation of nuclear receptors induces changed in cellular
function through the production of 2nd messengers. Correct
Answer False
Adenylate cyclase uses the substrate _____ to form the second
messenger chemical _____, and the increase in this second
messenger chemical causes the activation of the enzyme named
_____. Correct Answer ATP; cAMP; PKA
Adipose tissue stores lipid, but also has an endocrine function in
the release of cytokines and other types of chemical messengers
(hormones, etc). Correct Answer True
After a meal containing carbohydrates, circulating insulin levels
increase and circulation glucagon levels normally do not change.
Correct Answer False
All individuals who develop Metabolic Syndrome will
eventually develop type 2 diabetes Correct Answer False
An inhibitor of the serine kinase GSK-3beta will have all of the
following effects on insulin-resistant skeletal muscle except:
Correct Answer Cause increased insulin-stimulated glucose
transport.
Cause reduced serine kinase activity of GSK-3beta.
Cause decreased insulin-stimulated tyrosine phosphorylation.
Cause decreased serine phosphorylation of IRS-1 in the presence
of insulin.
ANG II has effects on blood pressure through its direct action to
cause vasoconstriction in peripheral vascular beds, as well as
,indirectly by its ability to cause increased secretion of
aldosterone from the adrenal cortex Correct Answer True
ANG II has effects on blood pressure through its direct action to
cause vasoconstriction in peripheral vascular beds, as well as
indirectly by its ability to cause increased secretion of
aldosterone from the adrenal cortex. Correct Answer True
APPL1 increases glucose transport in skeletal muscle cells by
interacting directly with the insulin receptor. Correct Answer
False
APPL1 increases glucose transport in skeletal muscle cells by
interacting directly with the insulin receptor. Correct Answer
False
As visceral adiposity begins to increase, there is a parallel
increase in the secretion and action of adiponectin. Correct
Answer False
As visceral adiposity begins to increase, there is a parallel
increase in the secretion and action of adiponectin. Correct
Answer False
Based on our limited body of knowledge regarding the details of
Alpha cell regulation during the development of type 2 diabetes,
which the following is FALSE? Correct Answer Just like β-
cells, under oxidative stress α-cells are targeted by the apoptotic
activity of caspases.
, Control of the level of gene transcription for the enzymes
PEPCK and G6Pase is the major mechanism for regulation of
gluconeogenesis. Which of the following signaling proteins are
NOT involved in the DOWN-regulation of gene expression for
PEPCK and G6Pase? Correct Answer PLC
Decreased in both circulating adiponectin levels and cellular
adiponectin receptor levels can contribute to reduced
adiponectin action and to the development of insulin resistance.
Correct Answer True
Decreases in both circulating adiponectin levels and cellular
adiponectin receptor levels can contribute to reduced
adiponectin action and to the development of insulin resistance.
Correct Answer True
During exercise or fasting, glucagon will mediate an increase in
HGP. Which of the following is NOT a mechanism by which
glucagon works to accomplish this?
A. It causes phosphorylation of glycogen phosphorylase.
B. It decreases G6Pase expression
C. It causes phosphorylation of phosporylase kinase
D. It increases cAMP levels Correct Answer B
Enzymes which remove phosphates from cellular proteins are
called __________, whereas enzymes which add phosphates to
cellular proteins are called __________. Correct Answer
phosphatases; kinases
Excess serine phosphorylation of IR and IRS in hepatocytes will
be associated with all of the the following EXCEPT: Correct
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