Intrinsic factor - Answers comes from inside the cell
What is the stem cell niche? - Answers -where stem cells reside
-varies among different organs and tissues
During which stage are embryonic stem cells found? - Answers the blastocyst stage
What are embryonic stem cells? - Answers pluripotent cells derived from the inner cell mass (ICM) of a
blastocyst
What is a blastocyst? - Answers a structure formed during the early development of mammals
-trophoblast cells + inner cell mass
-trophoblast cells will form the placenta
-ICM will develop into the embryo
What are the 3 germ layers of the inner cell mass? - Answers -endoderm
-mesoderm
-ectoderm
What are the characteristics of embryonic stem cells (2)? - Answers 1. long term culture (proliferate
indefinitely in vitro)
2. pluripotent (can differentiate into any cell type, can form a teratoma, can form chimeric organisms)
Test 1 for pluripotency - Answers induced differentiation: if cells are embryonic stem cells, they should
give rise to cell lineages from all 3 germ layers under different conditions. (this is b/c embryonic stem
cells are from the blastocyst stage, which is pluripotent)
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