Constipation - answer✔infrequent BM (<3x/week)
difficulty passing stool
chronic idopathic constipation (IBS-C) - answer✔ctsp for several weeks or longer with an
unknown cause
what is idopathic constipation associated with - answer✔chronic/recurrent abd discomfort
relieved by defecation
medical conditions that cause constipation - answer✔IBS-C
MS
PD
DM
cerebrovascular events
anal disorders-fissures, fistulas, rectal prolapse
spinal cord tumors
hypothyroidism
non-drug constipation tx - answer✔increasing fluids (>64 oz day)
increasing physical activity
high fiber foods
drugs that cause constipation - answer✔antacids (aluminium/calcium containing)
antidiarrheals
clonidine
colesevelam
anticholinergic effects
--> antihistamines, antispasmodics, phenothiazines, TCAs, urge incontinence drugs
iron
non-DHP CCB (esp verapamil)
opioids
sucralafate (has aluminium)
how long do we treat constipation with OTC drugs - answer✔7 days
bulk-forming laxatives MOA - answer✔absorb water into intestine soaking up fluid and adding
bulk to stool
--> increases peristalsis and decreases stool transit time
bulk-forming laxative products - answer✔psyllium (metamucil)
calcium polycarbophil (fiberCon)
methylcellulose (citrucel)
wheat dextrin (benefiber)
bulk-forming laxatives ADR - answer✔flatulence
abd cramping
bloating
bulk-forming laxatives DDIs - answer✔calcium polycarbophil needs to be separated from other
drugs because of binding interactions
osmotic laxative MOA - answer✔contain large molecules that are poorly absorbed that draw
fluid into bowel lumen through osmosis
--> distends colon, stimulates peristalsis
osmotic laxative products - answer✔magensium hydroxide (milk of magnesia)
PEG (miralax)
glycerin (fleet liquid/supp)
lactulose (constulose, enulose)
sodium phosphates (fleet enema)
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Brainbarter. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $10.49. You're not tied to anything after your purchase.
