3. moderately strong interaction affected by salt or change in pH. (increased salt -
> increased ions)
When pH is outside normal range, enzyme activity will _____. - ANSWERS-
decrease.
A misfolded protein: - ANSWERS-1. causes protein aggregation
2. can result from denaturation
3. can be degraded by the cell
4. will lose its normal function
Mutation of an active amino acid changes ____ - ANSWERS-an enzyme's ability to
bind a substrate.
,A dehydration reaction _______ a polypeptide, whereas a hydrolysis reaction
______ a polypeptide. - ANSWERS-A dehydration reaction builds a polypeptide,
whereas a hydrolysis reaction breaks a polypeptide.
During feedback inhibition, a molecule acts as an ____ for an enzyme in order
to________. - ANSWERS-During feedback inhibition, a molecule acts as an
inhibitor for an enzyme in order to prevent over production of a product.
Replacing a polar amino acid with a non-polar amino acid will likely cause
________. - ANSWERS-a neurodegenerative disease.
Characteristics of hemoglobin in the lung: - ANSWERS-1. Relaxed, planar state
2. Oxygenated - high affinity for O2
3. high pH, low CO2, low H+ ions
Characteristics of hemoglobin in the muscle: - ANSWERS-1. tense, domed state
2. low affinity for O2
3. low pH, High CO2, High H+ ions
Hemoglobin _____ to O2 at high pH and _______ O2 at low pH. - ANSWERS-
Hemoglobin binds to O2 at high pH and releases O2 at low pH.
(It binds at high pH in lung to pick up oxygen and carry it tissues and release it at
low pH.)
, These 3 things can be catabolized into Acetyl CoA - ANSWERS-1. fatty acids
2. amino acids
3. glucose
How many ATP are produced for every molecule of glucose that is aerobically
metabolized? - ANSWERS-30
What occurs in an exercising muscle under anaerobic conditions? - ANSWERS-
Pyruvate from glycolysis is turned into lactate in order to regenerate NAD+ for
further rounds of glycolysis, yielding 2 ATP per round for muscle use. The Cori
Cycle allows lactate to be turned into glucose via gluconeogenesis in the liver at
the expense of 6 ATP. Overall, the Cori Cycle creates a deficit of 4 ATP.
What happens if cyanide is consumed? - ANSWERS-ADP will build up, protons will
not pump into intermembrane, and oxygen will not be consumed by ETC.
What happens to pyruvate in the absence of oxygen? - ANSWERS-In the absence
of oxygen, pyruvate is transformed to lactate by fermentation.
The Cori Cycle occurs during ______. - ANSWERS-exercise.
During the Cori Cycle, lactate produced by fermentation leaves the cell and enters
the blood. The liver cells take up the lactate from the blood and use the
gluconeogensis pathway to convert 2 molecules of lactate back to glucose.
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