Pharmacology is defined as what? Answer - the study of drugs and their
interactions with living systems
therapeutics is defined as what? Answer - use of drugs to diagnose, prevent,
and treat illness and or pregnancy. it is the medical use to drugs
what is the most important property of a drug? Answer - its effectiveness
this property of an ideal drug states that even at a high concentration and for
long periods of administration; a drug must be safe? But there is no totally safe
drug. (non habit forming or side effects) Answer - Safety
this property of an ideal drug states that a drug must elicit only the response
for which it is given? (all drugs can cause side effects) Answer - Selectivity
an ideal drug would be expected to exhibit? Answer - predictability, selectivity,
and stability
match the right ADME to its location:
A= 1. Liver
D= 2. kidney
M= 3.bloodstream
E= 4. stomach
, 5. intestines Answer - A= stomach and intestines
D= Bloodstream
M= liver
E= liver and kidneys
what are the types of drug receptor interactions? Answer - covalent
(irreversible) and non covalent (reversible);
Alkylation, Acylation; Oxidation and reduction; and Phosphorylation are what
type of bond? Answer - irreversible inhibitions or covalent bond
what is the strongest non covalent receptor interaction? Answer - ionic.
Acids or amine drugs are easily ionized at physiological pH, and form ionic
bonds by? Answer - binding to receptor of opposite charges.
What are the amino acids that can cause ionic bonds with drug molecules?
Answer - His (Acid drug), Glu (basic drug), Lys (acid drug), Arg (acid drug), Asp
(basic drug)
is the second strongest non covalent bond? Accrues with mostly ketones,
esters, and amides Answer - dipole interactions
is a the third strongest non covalent bond that is the most common type of
drug interaction and a special type of Dipole-dipole bond? Answer - hydrogen
bond
within hydrogen bonding, all donors can be acceptors ; but? Answer - not all
acceptors can be donors.
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