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Exam 4: NURS 615/ NURS615 (Latest 2024/ 2025 Update) Advanced Pharmacotherapeutics Review |Qs & As| 100% Correct| Grade A (Verified Answers)- Maryville $10.99   Add to cart
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Exam 4: NURS 615/ NURS615 (Latest 2024/ 2025 Update) Advanced Pharmacotherapeutics Review |Qs & As| 100% Correct| Grade A (Verified Answers)- Maryville
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Exam 4: NURS 615/ NURS615 (Latest 2024/ 2025 Update) Advanced Pharmacotherapeutics Review |Qs & As| 100% Correct| Grade A (Verified Answers) Q: How does metformin work? Answer: Decreases hyperglycemia by decreasing hepatic glucose production called hepatic gluconeogenesis. The average pe...

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  • September 30, 2024
  • 27
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • NURS 615/ NURS615
  • NURS 615/ NURS615

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ExamI4:INURSI615/INURS615I(LatestI2024
/I2025IUpdate)IAdvancedI
PharmacotherapeuticsIReviewI|QsI&IAs|I
100%ICorrect|IGradeIAI(VerifiedIAnswers)

Q:IHowIdoesImetforminIwork?

Answer:
DecreasesIhyperglycemiaIbyIdecreasingIhepaticIglucoseIproductionIcalledIhepaticIgluconeogen
esis.ITheIaverageIpersonIwithItypeI2IdiabetesIhasIthreeItimesItheIrateIofIgluconeogenesis,Imet
forminItreatmentIreducesIthisIbyIoverI1/3rd.ITheImolecularImechanismIofImetforminIisn'tIcom
pletelyIunderstood.IInIadditionItoIsuppressingIhepaticIglucoseIproduction,ImetforminIincreases
IinsulinIsensitivity,IenhancesIperipheralIglucoseIuptakeIbyIinducingItheIphosphorilizationIofIgl
u4IenhancerIfactor,IdecreasesIinsulinIinducedIsuppressionIofIfattyIacidIoxidation,IandIdecrease
sIabsorptionIofIglucoseIfromItheIGIItract.IAlsoIofInote**IMetforminIhelpsIreduceILDLIcholes
terolIandItriglycerideIlevelsIandIisInotIassociatedIwithIweightIgain,IinIsomeIpeopleIitIhelpsIpr
omoteIweightIloss**




Q:IWhatIdiagnosticItestingIisIrequiredIbeforeIandIthroughoutItherapyIwithImetformin?

Answer:
MetforminIisInotImetabolized,IitIisIclearedIfromItheIbodyIbyItubularIsecretionIandIisIsecretedI
unchangedIinItheIurine.IMetforminIisIundetectableIinIbloodIplasmaIwithinI24IhrsIofIaIsingleIo
ralIdoseItheIaverageIeliminationIhalf-
lifeIinIplasmaIisI6.2IhrsIasIitIisIsecretedIinItheIurineIyouIshouldIcheckIaIserumIcrtItoIassessIre
nalIfunction.




Q:IWhatIisItheIactionIofIgliptin?

Answer:

,TheImechanismIofIDDP-
4IinhibitorsIisItoIincreaseIincretinIlevelsIincretinIareIGLP1IandIGIPIwhichIinhibitIglucagonIrel
easeIinIwhichIinIturnIincreasesIinsulinIsecretion,IdecreasesIgastricIemptying,IandIdecreasesIblo
odIglucoseIlevels




Q:IHowIdoIGLPIagonistsIwork?

Answer:
TheyIbindIdirectlyItoIaIreceptorIinItheIpancreaticIbetaIcell.ITheseIagentsIworkIinItheIsameIpat
hwayIasItheIDPP-4IinhibitorsIasImentionedIaboveIbutIareIgenerallyIconsideredImoreIpotent.




Q:IWhenIshouldIexenatideIbeIadministered?

Answer:
60IminutesIpriorItoItheImorningIandIeveningImeal




Q:IHowIwillIyouIassessIforIgranulocytopenia?

Answer:
SignsIofIaIColdIorIfluIincludingIfeverIandIsoreIthroat




Q:IWhatIareItheIadverseIeffectsIofIpropylthiouracil?

Answer:
Agranulocytosis,Ithrombocytopenia,IandIfulminantIliverIfailureIasIstatedIabove,Ipt'sIonIPTUIw
henItheyIdevelopIfeverIorIsoreIthroat,IitIwouldIbeIimportantItoIcheckIaICBCIpreferablyIwithIa
IsmearIandIaIdiff.

, Q:IWhatIareItheIadverseIeffectsIofIlevothyroxine?

Answer:
TachycardiaIandIanginaIinItheIelderly




Q:IAIpatientIdevelopsIaItoxicIgoiter.IWhatIisItheIrecommendedItreatment?

Answer:
MethimazoleIforIoneImonthIthenIradioactiveIiodineI(p.I641)




Q:IWhatIareItheIadverseIeffectsIofIPTUIandImethimazole?

Answer:
PTU-IFatalIagranulocytopeniaIlookIforIfeverIandIsoreIthroatIandITEMPORARYIALOPECIA




Q:IWhatIisItheIactionIofIbiphosphonates?

Answer:
BoneIundergoesIconstantIturnoverIandIisIkeptIinIbalanceIbyIosteoblastsIcreatingIboneIandIoste
oclastsIdestroyingIbone.IBisphosphonatesIinhibitItheIdigestionIofIboneIbyIencouragingIosteocl
astsItoIundergoIapoptosisIorIcellIdeathIthereIbyIslowingIboneIloss.IOralIbisphosphonatesIcanIc
auseIupsetIstomachIandIinflammationIasIwellIasIerosion.IErosionsIofItheIesophagusIwhichIisIt
heImainIproblemIofIoralIandIcontainingIpreparations.IThisIcanIbeIpreventedIbyIsittingIuprightI
forI30-
60IminutesIafterItakingItheImedication.IIfItheIpatientIdoesIdevelopIsomeItypeIofIgastricIdistres
s,IgiveIthemIoralI30mlIofIMaaloxI3IhrsIafterItakingIit.IIVIbisphosphonatesIcanIgiveIfeverIandI
fluIlikeIsymptomsIafterItheIfirstIinfusionIwhichIisIthoughtItoIoccurIbecauseIofItheirIpotentialIt
oIactivateIhumanITIcells

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