How much % CO do the kidneys recieve? - Answer 20-25%
"filters essential substances and reabsorbs substances needed to maintain normal
composition" describes what organ? - Answer the KIDNEY!
SATA: Which of the following mechanisms controls RBF?
a. intrinsic
b. autoregulation
c. extrinsic
d. protein & glucose
e. sympathetic controls - Answer a, c, d
Intrinsic, extrinsic and protein and glucose
Of the intrinsic regulation of RBF, the juxtaglomerular complex contains _________
necessary to convert angiotensinogen to angiotensin I - Answer Renin
What RBF intrinsic regulation mechanism has this function:
"plays essential feedback role in linking ABP and RBF to GFR" - Answer Juxtaglomerular
complex
How does a sympathetic NS stimulating event like shock or trauma affect RBF? - Answer
Afferent and Efferent arteriole constriction --> decreased RBF, GFR --> decreased UOP
What affect do the blood borne hormones angiotensin II, ADH, endothelins have on
RBF? - Answer vasoCONSTRICTION
,What affect do the blood borne hormones dopamine, nitric oxide, prostaglandinds have
on RBF? - Answer vasoDILATION
[T/F]: NSAIDS INCREASE RBF - Answer False!
NSAIDS inhibit prostaglandin synthesis --> decreased RBF and GFR
How does a decreased GFR affect Na + Cl? - Answer increased Na + Cl reabsorption -->
decreased Na + Cl to the macula densa
What are the results of decreased Na + Cl to the macula densa? - Answer 1. decreased
resistance in afferent arterioles --> increased GFR
2. increased renin release from JG cells
Describe how protein and glucose affects RBF - Answer amino acids and Na absorbed
together --> decreased Na to macula densa --> JG cell activation --> increased RBF
Where are the glomeruli and convoluted tubules located? - Answer in the cortex
Renal pyramids, loop of henle, renal pelvis and collecting system are located ________ -
Answer in the medulla
Afferent arteriole is supplied by ________ - Answer interlobar ARTERY
Efferent arteriole is supplied by ________ - Answer interlobar VEIN
Where are most nephrons located? - Answer 85% are cortical
(short distance)
,The juxtamedullary nephrons are the primary site of __________ __________________ -
Answer urine concentration
[T/F]: the glomerulus is a low pressure capillary filtration system - Answer FALSE - it is
HIGH pressure
due to the hydrostatic pressure
_________ is protein free plasma - Answer Filtrate
[T/F]: blood flows IN the Afferent arteriole and OUT of the Efferent arteriole - Answer
TRUE
"A comes before E"
Efferent arteriole --> peritubular capillaries is a low pressure system adapted for
______________ - Answer Reabsorption
[SATA]: Which of the following PASSIVELY diffuses in the nephron tubules?
a. sodium
b. glucose
c. water
d. potassium
e. chloride
f. urea
g. phosphate
h. calcium
i. amino acids - Answer c, f
water and urea
[SATA]: Which of the following ACTIVE diffuses in the nephron tubules?
Describe how normal UOP (60 mL urine/ hr) is calculated? - Answer GFR = 125 mL/ min
Reabsorption of H2O = 124 mL/ min
Which of the following drains the Bowman's capsule?
a. proximal convoluted tubule
b. ascending loop of henle
c. distal convoluted tubule
d. collecting tubule - Answer a. proximal convoluted tubule
At which of the following places does 65% of glucose, amino acids and electrolytes get
absorbed?
a. proximal convoluted tubule
b. ascending loop of henle
c. distal convoluted tubule
d. collecting tubule - Answer a. proximal convoluted tubule
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