When a patient presents with myxedema coma, which one of the following groups
of symptoms may be present? - Correct Answer-Hypothermia, thickening of the
tongue, and disorientation-due to longstanding low level of thyroid hormone
Which of the following is NOT associated with Hashimoto's thyroiditis? - Correct
Answer-Weight loss-this is usually noted in hyperthyroidism
Striae, skin atrophy, and purpura may be associated with: - Correct Answer-
Cushing's Disease-also moon facies & buffalo hump
A 20-year-old with acanthosis nigricans should be evaluated for: - Correct
Answer-Diabetes mellitus-skin condition characterized by dark velvety patches in
the body folds or creases
Thyrotoxicosis is most commonly associated with: - Correct Answer-
Hyperthyroidism
,When patients administer regular insulin (Humulin R U-500), they should be
taught: - Correct Answer-10 units of Humulin R U-500 is equal to 10 units on a U-
500 insulin syringe.
Radioiodine therapy is safe to administer to: - Correct Answer-A 30-year-old man
who desires natural fatherhood-used to tx hyperthyroidism and does not cause
infantility or birth defects in the offspring of tx'd pts
A pt who has Addison's disease has received a prescription for fludrocortisone.
Fludrocortisone acts by: - Correct Answer-Regulating salt and water balance-
mineralocorticoid indicated as partial replacement therapy for pts with primary
or 2ndary adrenocortical insufficiency
Methimazole for the tx of Graves' disease is contraindicated in pts: - Correct
Answer-Who are pregnant-can cause fetal harm when administered, can readily
cross the placental membranes
Which of the following medications may cause gynecomastia? - Correct Answer-
Enalapril (Vasotec)-ACE inhibitors may cause gynecomastia
A pt is started on a sulfonylurea (i.e. glyburide). The NP informs the pt that
sulfonylureas are likely to: - Correct Answer-Reduce microvascular events-also
low in cost
, Disadvantages-produce hypoglycemia and cause weight gain
Thiazolidinedione (TZD) medications: - Correct Answer-Increase insulin sensitivity-
by acting on adipose, muscle & liver to increase glucose utilization and decrease
glucose production
Pts taking dipeptidyl-peptidase-4 (DDP-IV) inhibitors for the tx of T2DM do NOT
routinely need to be monitored for: - Correct Answer-Weight loss-Januvia,
Onglyza, Tradjenta not likely to cause weight loss or weight gain
The expected hemoglobin A1V reduction for pts who are started on dipeptidyl-
peptidase-4 (DDP-IV) inhibitors such as sitagliptin (Januvia) is: - Correct Answer-
0.6%
DDP-IV inhibitors such as alogliptin (Nesina): - Correct Answer-Suppress glucagon
secretion and increase insulin secretion
Sulfonylurea-stimulate the release of insulin from functioning beta cells
Biguanides-decrease hepatic glucose production, decrease intestinal absorption
of glucose, and improve insulin sensitivity
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