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Pathophysiology Exam 1 Questions With Verified Answers

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©BRAINBARTER 2024/2025 Pathophysiology Exam 1 Questions With Verified Answers Stages of general adaptation syndrome - answer1. Alarm Initial reaction Sympathetic nervous system 2. Resistance Adaptation Limit stressor 3. Exhaustion Adaptation failing Disease develops Edema - answerExces...

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  • October 2, 2024
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  • 2024/2025
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  • Pathophysiology
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Pathophysiology Exam 1 Questions With
Verified Answers


Stages of general adaptation syndrome - answer✔1. Alarm
Initial reaction
Sympathetic nervous system


2. Resistance
Adaptation
Limit stressor


3. Exhaustion
Adaptation failing
Disease develops

Edema - answer✔Excess fluid in the interstitial space

Dehydration (ECF volume deficit) - answer✔Can occur independently without electrolyte
defects
Decrease in fluid level leads to increase in level of blood solutes
Cell shrinkage
Hypotension

Hypovolemia or fluid volume deficit - answer✔Decreased fluid in the intravascular space

Hypotonic Hydration - answer✔(fluid overload)

Causes of Fluid Deficit - answer✔Inadequate fluid intake

, ©BRAINBARTER 2024/2025


Poor oral intake
Inadequate IV fluid replacement


Excessive fluid or sodium losses:


Gastrointestinal losses Excessive diaphoresis Prolonged hyperventilation Hemorrhage Nephrosis
Diabetes mellitus Diabetes insipidus Burns Open wounds Ascites Effusions Excessive use of
diuretics Osmotic diuresis

Deydration Manisfestations - answer✔thirst, altered level of consciousness, hypotension,
tachycardia, weak and thready pulse, flat jugular veins, dry mucous membranes, decreased skin
turgor, oliguria, weight loss, and sunken fontanelles

Cancer Benign - answer✔Slow, progressive, localized, well defined, resembles host (more
differentiated), grows by expansion, does not usually cause death

Cancer Malignant - answer✔Rapid growing, spreads (metastasis) quickly, fatal, highly
undifferentiated

Sodium - answer✔Normal range: 135-145 mEq/L.
• Most significant cation and prevalent electrolyte of extracellular fluid.
• Controls serum osmolality and water balance. Plays a role in acid-base balance.
• Facilitates muscles and nerve impulses.
• Main source is dietary intake.
• Excreted through the kidneys and gastrointestinal tract.

Hypernatremia - answer✔Sodium > 145 mEq/L
Serum osmolarity increases
• Results in fluid shifts

Causes of Hypernatremia - answer✔Excessive sodium ingestion Hypertonic IV saline (3%
saline) administration
Cushing's syndrome
Corticosteroid use
Diarrhea

, ©BRAINBARTER 2024/2025


Excessive sweating
Prolonged episode of hyperventilation
Diuretic use Diabetes insipidus
Decreased water ingestion
Loss of thirst sensation
Inability to drink water
Third spacing
Vomiting

Hypernatremia Manifestations: - answer✔increased temperature, warm and flushed skin, dry and
sticky mucous membranes, dysphagia, increased thirst, irritability, agitation, weakness,
headache, seizures, lethargy, coma, blood pressure changes, tachycardia, weak and thready pulse,
edema, and decreased urine output

Hyponatremia - answer✔Sodium < 135 mEq/L
Serum osmolarity decreases

Causes of Hyponatremia - answer✔Deficient sodium
Diuretic use
Gastrointestinal losses
Excessive sweating
Insufficient aldosterone levels
Adrenal insufficiency
Dietary sodium restrictions
Excessive water
Hypotonic intravenous saline (0.45% saline) Hyperglycemia
Excessive water ingestion
Renal failure
Syndrome of inappropriate antidiuretic hormone Heart failure

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