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Biosafety & Biosecurity Study Guide Exam And Actual Answers.

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  • Biosafety And Biosecurity

BMBL - Answer Biosafety in Microbiological and Biomedical Laboratories a set of guidelines for the safe handling and containment of biological agents -established by the CDC and NIH Biological Agents - Answer Infectious microorganisms and potentially hazardous biological materials Ri...

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  • October 3, 2024
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Biosafety & Biosecurity Study Guide
Exam And Actual Answers.
BMBL - Answer Biosafety in Microbiological and Biomedical Laboratories

a set of guidelines for the safe handling and containment of biological agents

-established by the CDC and NIH



Biological Agents - Answer Infectious microorganisms and potentially hazardous biological materials



Risk Assessment - Answer process that enables the appropriate selection of microbiological practices,
safety equipment, and facility safeguards that can prevent laboratory-associated infections (LAIs)



LAI - Answer Laboratory-Associated Infections



How has the rate of Laboratory-Associated Infections decreased? - Answer Improvements in
containment equipment, engineering controls, and a greater emphasis on safety training



What are the primary risk criteria - Answer • Infectivity

• Severity of disease

• Transmissibility

• Nature of the work being conducted

• Agent origin - for agents that cause moderate to severe disease



What are common ways of developing LAIs? - Answer exposure to contaminated aerosols and droplets



Biological Risk Assessment - Answer • Staff's training and technical experience

• Activities that might lead to staff exposure

• Probability that agent exposure will lead to a LAI

• Availability of preventive measures and effective treatments for the disease

, • Consequences of an infection



How are infectious agents classified by NIH? - Answer into ascending risk groups from 1-4

-higher # indicates higher risk of hazardous characteristics that may cause human disease



How are infectious agents classified by WHO? - Answer based on degree of Dz hazard to humans and
animals, natural route of the Dz's transmission, preventative measures, and effective treatments



WHO - Answer World Health Organization



Genetically Modified Agent Hazards - Answer possibility that the genetic modification could increase an
agent's pathogenicity or affect its susceptibility to effective tx



Dangers of Aerosols - Answer typically undetected and are extremely pervasive

-those containing infectious particles are hazardous even when inhalation may not be a natural route of
transmission of disease



Most important element of containment - Answer strict adherence to standard microbiological
practices and techniques



What are examples of primary barriers? - Answer Safety Equipment and PPE:

-Biological Safety Cabinet

-gloves, safety glasses, gowns, shoe covers



• Class I and II BSC - Answer protection to both the lab personnel and environment when used with
good microbiological practices



Class II & III BSC - Answer protects research materials from airborne contaminants by using a HEPA
filter



BSC class 1 - Answer Personnel and Environmental Protection only!

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