1. Humoral immunity: Soluble products in body fluids were responsible for immune
protection (anti-serum)
2. Cellular immunity: Specialized cells had the capacity to neutralize and engulf
infectious agents
, Two philosophies of immunology
Illness can be transmitted by microorganisms
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Germ theory of disease
- Regarded as the father of vaccination (though he was not the first to inoculate
cowpox as smallpox prevention)
- Noted that milkmaids rarely developed smallpox
- Rationalized that exposure to cowpox could prevent smallpox
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Edward Anthony Jenner
Proposed the idea that cells which ate bacterium (phagocytes) were responsible for
immune protection
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Elie Metchnikoff
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