Are there more naive memory cells or pathogen-specific memory cells?
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Pathogen-specific memory cells far outnumber their naive counterparts
, Secondary response
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1. Large number of pathogen-specific cells respond immediately
2. Pathogen-specific antibodies already present
3. Antibodies are isotype-switched and have high affinity for the pathogen
4. Lower threshold of activation
5. Effector T cells are present and can enter infected tissue immediately
6. Close cooperation between innate and adaptive immunity from the start
Why does the amount of circulating pathogen-specific antibodies usually decrease
over time?
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Most plasma cells made in the primary response are short-lived
What is the advantage in a secondary immune response?
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Memory cells
Describe the difference between the immune response to a first infection with a
pathogen to that of a second infection with the same pathogen.
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