TestWBankWforW
McCanceW&WHue
ther’sWPathophysio
logy:WTheWBiologi
cWBasisWforWDise
aseWinWAdultsWan
dWChildrenW9thW
EditionWbyWJulia
WRogers
1
, PATHOWPHY
SIOLOGYW9T
H
EDITIONW
MCCANCE
WTESTWB
ANK
LATESTWREVISED
,ChapterW1:WCellularWBiology
MULTIPLEWCHOICE
1. WhichWcomponentWofWtheWcellWprodNuUceRsSIhNyGdTroBg.CeO
nWM
peroxideW(H 2O 2)Wby
WusingWoxygenWtoWremoveWhydrogenWatomsWfromWspecificWsubstratesWi
nWanWoxidativeWreaction?
a. Lysosomes c. Ribosomes
b. Peroxisomes d.W Oxyhydrosomes
ANS:WB
PeroxisomesWareWsoWnamedWbecauseWtheyWusuallyWcontainWenzymesWthatWus
eWoxygenWtoWremoveWhydrogenWatomsWfromWspecificWsubstratesWinWanWoxid
ativeWreactionWthatWproducesWH2O2,WwhichWisWaWpowerfulWoxidantWandWpot
entiallyWdestructiveWifWitWaccumulatesWorWescapesWfromWperoxisomes.WRiboso
mesWareWRNA-
proteinWcomplexesW(nucleoproteins)WthatWareWsynthesizedWinWtheWnucleolusWa
ndWsecretedWintoWtheWcytoplasmWthroughWporesWinWtheWnuclearWenvelopeWca
lledWnuclearWporeWcomplexes.WLysosomesWareWsaclikeWstructuresWthatWoriginat
eWfromWtheWGolgiWcomplexWandWcontainWmoreWthanW40WdigestiveWenzymes
WcalledWhydrolases,WwhichWcatalyzeWbondsWinWproteins,Wlipids,WnucleicWacids
,WandWcarbohydrates.WOxyhydrosomesWareWinvolvedWinWenzymeWproduction.
PTS:WWW 1 REF:WPageW8
2. WhichWstatementWbestWdescribesWtheWcellularWfunctionWofWmetabolicWabsorption?
a. CellsWcanWproduceWproteins. c. CellsWcanWtakeWinWandWuseWnutrients.
b. CellsWcanWsecreteWdigestiveWenzymes. d.W CellsWcanWsynthesizeWfats.
ANS:WC
InWmetabolicWabsorption,WallWcellsWtakeWinWandWuseWnutrientsWandWotherW
substancesWfromWtheirWsurroundings.WTheWremainingWoptionsWareWnotWinclusi
veWinWtheirWdescriptionsWofWcellularWmetabolicWabsorption.
PTS:WWW 1 REF:WPageW2
3. MostWofWaWcell’sWgeneticWinformation,WincludingWRNAWandWDNA,WisWcontainedWin
Wthe:
a. Mitochondria c. Nucleolus
b. Ribosome d.WWW Lysosome
ANS:WC
TheWnucleusWcontainsWtheWnucleolus,WaWsmallWdenseWstructureWcomposedWl
argelyWofWRNA,WmostWofWtheWcellularWDNA,WandWtheWDNA-
bindingWproteins,WsuchWasWtheWhistones,WwhichWregulateWitsWactivity.WTheW
otherWoptionsWdoWnotWcontainWmostWofWaWcell’sWgeneticWinformation.
PTS:WWW 1 REF:WPageW2
4. WhichWcellWcomponentWisWcapableWofWcellularWautodigestionWwhenWitWisW
releasedWduringWcellWinjury?
a. Ribosome c. SmoothWendoplasmicWreticulum
b. GolgiWcomplex
d.WLysosomesWANS:WD
, TheWlysosomalWmembraneWactsWasWaWprotectiveWshieldWbetweenWtheWpowerf
ulWdigestiveWenzymesWwithinWtheWlysosomeWandWtheWcytoplasm,WpreventingW
theirWleakageWintoWtheWcytoplasmicWmatrix.WDisruptionWofWtheWmembraneWb
yWvariousWtreatmentsWorWcellularWinjuryWleadsWtoWaWreleaseWofWtheWlysoso
malWenzymes,WwhichWcanWthenWreactWwithWtheirWspecificWsubstrates,Wcausing
WcellularWself-
digestion.WTheWotherWoptionsWdoWnotWcorrectlyWdescribeWthisWprocess.
PTS:WWW 1 REF:WPagesW7-8
5. WhatWisWtheWsequenceWofWstepsWinWtheWdevelopmentWofWaWdigestiveWen
zymeWbyWtheWpancreasWcellsWfromWtheWinitialWtranscriptionWtoWtheWreleas
eWfromWtheWcell?
a. TheWenzymeWisWtranscribedWfromWDNAWbyWRNAWinWtheWnucleu
s,WproceedsWtoWtheWribosomeWforWsynthesis,WandWisWtransportedW
inWaWsecretoryWvesicleWtoWtheWcellWmembrane.
b. TheWenzymeWisWtranscribedWfromWRNAWbyWDNAWinWtheWnucleus,W
proceedsWtoWtheWlysosomeWforWsynthesis,WandWisWtransportedWinWan
WencapsulatedWmembraneWtoWtheWcellWmembrane.
c. TheWenzymeWisWtranscribedWbyWtheWmitochondriaWinWtheWnucleus,W
proceedsWtoWtheWribosomeWforWsynthesis,WandWisWtransportedWinWaW
cytoskeletonWtoWtheWcellWmembrane.
d. TheWenzymeWisWtranscribedWfromWDNAWbyWRNAWinWtheWnucleus,
WproceedsWtoWtheWGolgiWcomplexWforWsynthesis,WandWisWtransported
WinWaWcytosolWtoWtheWcellWmembrane.
ANS:WA
TheWenzymeWisWtranscribedWfromWDNAWbyWRNAWinWtheWnucleus,Wproce
edsWtoWtheWribosomeWforWsynthesis,WandWisWtransportedWinWaWsecretoryW
vesicleWtoWtheWcellWmembrane.WTheWotherWoptionsWdoWnotWcorrectlyWdes
cribeWthisWprocess.
NURSINGTB.COM
PTS:WWW 1 REF:WPageW7W|WFigureW1-5
6. DuringWwhichWphaseWofWtheWcellWcycleWisWDNAWsynthesized?
a. G1 c. G2
b. S d.W M
ANS:WB
TheWfourWdesignatedWphasesWofWtheWcellWcycleWare:W(1)WtheWG1WphaseW(
GW=Wgap),WwhichWisWtheWperiodWbetweenWtheWMWphaseW(MW=Wmitosis)W
andWtheWstartWofWDNAWsynthesis;W(2)WtheWSWphaseW(SW=Wsynthesis),Wduri
ngWwhichWDNAWisWsynthesizedWinWtheWcellWnucleus;W(3)WtheWG2Wphase,Wd
uringWwhichWRNAWandWproteinWsynthesisWoccurs,WtheWperiodWbetweenWtheW
completionWofWDNAWsynthesisWandWtheWnextWphaseW(M);WandW(4)WtheWM
Wphase,WwhichWincludesWnuclearWandWcytoplasmicWdivision.
PTS:WWW 1 REF:WPageW37
7. WhatWorganicWcompoundWfacilitatesWtransportationWacrossWcellWmembranes
WbyWactingWasWreceptors,WtransportWchannelsWforWelectrolytes,WandWenzy
mesWtoWdriveWactiveWpumps?
a. Lipids c. Proteins
b. Proteases d.W Carbohydrates