BGEN 3022 Midterm Questions and Correct Answers | Latest Update
0 view 0 purchase
Course
BGEN 3022
Institution
BGEN 3022
genome
complete DNA sequence of a cell or organism
- 2 in humans: nuclear, mitochondrial
mitochondrial genome
- Very small (16.6kb long)
- No histones
- Highly redundant
- Compact (no 'extra' DNA)
- DS ring
- Each mito has multiple copies of the mtDNA genom...
- can adopt complex secondary and tertiary folding structures
- i.e., XIST
miRNAs
micro RNAS
- important regulators of gene expression
o negative regulators via translational repression or mRNA degradation
~ 1 ~ for inquiry mail me @ supergrades12@gmail.com
, Best Grades | Must Pass | Latest Update | Correct Answers | 2024/ 2025
o Bind complementary 3'UTRs of target mRNAs
- >1000 in human genome
- Small genes (22nt long)
- Infrequently mutated
- Revealed through C. elegans mutations (lin-4, let-7)
o Identified only in large scale screens via phenotypes
- Mutations Linked to certain human disease
o Hearing loss, keratoconus, cancer, obesity
§ Same inheritance patterns as mutations in protein-encoding genes
snRNA
small nuclear RNA
- Diverse family involved in splicing events
snoRNAs
small nucleolar RNA
- Guide processing of mainly rRNAs (>400)
gene families
~ 1 ~ for inquiry mail me @ supergrades12@gmail.com
, Best Grades | Must Pass | Latest Update | Correct Answers | 2024/ 2025
multiple copies of closely related genes that arose from a single ancestral
gene
- Members = paralogues
- Often found in clusters on Xm
- Arise through duplication events
5 mechanism of duplication
- unequal recombination
- chromosomal translocation
- DNA polymerase slippage
- transposable elements
- whole genome duplication
unequal recombination
repetitive sequences/confusion during recombination leads to unequal
crossing over
- primary mechanism of duplication
- net gain AND loss of DNA
- involves small OR large regions
- helps explains clusters at same chromosomal location
~ 1 ~ for inquiry mail me @ supergrades12@gmail.com
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Apluss. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $14.49. You're not tied to anything after your purchase.
