Exam (elaborations)
NURS 5334 ADV. PHARMACOTHERAPEUTICS, FINAL REVIEW
- Course
- Institution
NURS 5334 ADV. PHARMACOTHERAPEUTICS, FINAL REVIEW
[Show more]
Content preview
NURS 5334 ADV.PHARMACOTHERAPEUTICS, FINAL
REVIEW
Why0do0many0medications0lack0pediatric0dosing0information0in0their0drug0labeling?
A.0Most0medications0are0not0used0in0pediatric0patients.0
B.0There0is0a0lack0of0evidence-
based0literature0on0the0safe0and0effective0use0of0medications0in0children.
C.0The0FDA0does0not0allow0pediatric0dosing0information0in0product0labeling.0
D.0Only0products0available0as0oral0liquid0formulations0are0required0to0contain0pediatric0d
osing0information0in0their0labeling.0-0ans--✔✔B.0There0is0a0lack0of0evidence-
based0literature0on0the0safe0and0effective0use0of0medications0in0children.
Why0are0Neonates0at0greater0risk0for0toxicity0with0highly0protein-bound0drugs?0
A.0Protein0binding0is0decreased0in0neonates0increasing0the0amount0of0free0drug0availabl
e.0
B.0The0protein-bound0drugs0are0not0eliminated0effectively0in0neonates.0
C.0Neonates0are0unable0to0metabolize0these0highly0protein-bound0drugs.0
D.0Protein0binding0is0increased0in0neonates,0making0measurement0of0serum0levels0of0the
0drug0inaccurate.0-0ans--
✔✔A.0Protein0binding0is0decreased0in0neonates0increasing0the0amount0of0free0drug0avail
able.
At0what0age0are0adult0levels0of0renal0function0achieved?0•
A.060months0
B.0120months0
C.0240months0
D.030years0old0-0ans--✔✔B.0120months
What0is0the0list0that0identifies0drugs0with0a0high0likelihood0of0causing0adverse0effects0in0t
he0elderly?0
A.0No0use0list0
B.0Beers0list0
C.0Pharmacists0list0
D.0Adverse0drug0list0-0ans--✔✔B.0Beers0list
, In0pediatric0patients0gastric0acidity0does0not0reach0adult0values0for0______0-0ans--
✔✔20Years
The0principles0underlying0complication0to0drug0therapy0in0the0elderly0include___,0____,0_
___,0and0____.0-0ans--
✔✔altered0pharmacokinetics,0multiple0and0severe0illnesses,0multiple-
drug0therapy,0and0poor0adherence.
Altered0absorption0of0drugs0in0the0elderly0may0result0in____drug0response0-0ans--
✔✔Delay
The0four0major0factors0that0can0alter0drug0distribution0in0the0elderly0include0_,0_,0_,0and0_
?0-0ans--
✔✔increased0body0fat,0decreased0percentage0of0lean0body0mass,0decreased0total0body0
water,0and0reduced0concentration0of0serum0albumin.
The0most0important0cause0of0adverse0drug0reactions0in0the0elderly0is___.0-0ans--
✔✔drug0accumulation0secondary0to0reduced0renal0excretion.
In0the0elderly,0the0proper0index0of0renal0function0is____.0-0ans--
✔✔creatinine0clearance0or0GFR
Name0factors0underlying0the0increase0in0adverse0reactions0in0the0geriatric0population:0-
0ans--✔✔•0Polypharmacy0
•0Severe0illness,0
•0multiple0pathologies,0
•0greater0use0of0drugs0that0have0a0low0therapeutic0index
•0Inadequate0supervision0
•0Poor0patient0adherence
What0is0maximum0amount0of0Sumatriptan0that0can0be0taken0in010day?0
A.01000mg0
B.02000mg0
C.03000mg0
D.04000mg0-0ans--✔✔B.02000mg
The0ability0of0the0anesthetic0to0penetrate0the0axon0membrane0is0determined0by030propert
ies.0What0are0they?0
A.0Molecular0size0
B.0Protein0binding0potential0
C.0Lipid0solubility0
D.0Degree0of0ionization0at0tissue0pH0
E.0Water0solubility0
F.0Degree0of0blood0flow0-0ans--✔✔A.0Molecular0size0
C.0Lipid0solubility0
D.0Degree0of0ionization0at0tissue0pH
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller AGRADEPROMASTER. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $14.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
79276 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now