Chamberlain University NR- 565
Advanced Pharmacology
Fundamentals 2024 – 2025 NR- 565
Final Exam Week 5 and 6 Review
Study Guide
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-TSH - used primarily for screening
and diagnosing hypothyroid and
for monitor- ing replacement
therapy in hypothyroid patients
-T4 - Used to monitor thyroid
Thyroi hormone replacement therapy
d and to screen for
o Diagnosis & Evaluation thyroid dysfunction
What labs are used to -T3 - Useful in the diagnosis of
diagnose? hyper- thyroidism; can also be
used to monitor hormone
replacement therapy
-TSH low
-T4 normal
-T3 is high = hyperthyroidism
Thyroid Recheck TSH 6-8 weeks after
o Diagnosis & Evaluation initiating therapy and after any
dosage change; Check TSH at
Timeframe for re-check of labs least once a year after serum TSH
after starting levothyroxine? is stabilized
Hypothyroidism: Depend on
severity.
o Mild: subtle and may go
unrecognized
Thyroid o Moderate to severe:
o Diagnosis & Evaluation -Face is pale, puffy, and
expressionless.
Signs and symptoms of -Skin cold and dry.
hypothy- roidism? -Hair is brittle and hair loss occurs.
-Slowed Heart rate.
-Patient may complain of
lethargy, fa- tigue, and
-Temperature is lowered &
,intolerant to cold.
-Thyroid Enlargement may
occur if re- duced levels of
T3
and T4
Mentation may be impaired.
, o Elevated Heart rate and strong,
and dysrhythmias and angina may
develop
o The CNS is stimulated, resulting
is ner- vousness, insomnia, rapid
thought flow, and rapid speech,
Thyroid
hyperreflexia, tremors
o Diagnosis & Evaluation
o Skeletal muscles may weaken
and at- rophy
Signs and symptoms of
o Metabolic rate is raised,
hyperthy- roidism?
resulting in health and skin that
is warm and moist
o Feeling Hot + Heat intolerance
o Appetit is increased but fails to
match metabolic rate resulting in
weight loss
o All of these signs are referred
to as thyrotoxicosis
o Also usually present with
exophthal- mos - bulging of the
eyes
Characterized by profound
hyperther- mia (105 degrees F or
higher), severe tachycardia,
Thyroid restlessness, agitation, and
o Treatment tremor.
Unconsciousness, coma,
Treatment of thyroid hypotension, and heart failure
storm? may ensure.
These symptoms are produced by
ex- cessive levels of thyroid
hormone Thyroid crisis can be life
threatening and requires
immediate treatment.
o High doses of potassium iodide
or strong iodine solution are
given to sup- press thyroid
hormone release.
o Methimazole is given to
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