Exam (elaborations)
Pathoma High Yields – Questions & Complete Solutions
- Course
- Institution
Pathoma High Yields – Questions & Complete Solutions
[Show more]
Content preview
Pathoma High Yields – Questions & Complete SolutionsWhere is vWF derived from? Right Ans - Weibel-Palade bodies of
endothelial cells and alpha granules of platelets
Where does iron absorption occur? Right Ans - In the duodenum where the
enterocytes have DMT1 heme transporters
What is sideroblastic anemia? Right Ans - Anemia due to defective
protoporphyrin synthesis
Thalassemia patients have a causative inherited mutation that protects them
against what? Right Ans - Plasmodium falciparum malaria
What typically causes Alpha-Thalassemia?
What typically causes Beta-Thalassemia? Right Ans - Alpha = GENE
DELETION
Beta = GENE MUTATIONS
What do the electrophoresis results from a Beta-Thalassemia major patient
show? Right Ans - Little or no hemoglobin alpha
What presents as a crew cut appearance on x-ray? Right Ans - This is
massive erythroid hyperplasia causing expansion of hematopoiesis into the
skull which can occur in alpha and beta thalassemia.
Where is folate absorbed? Right Ans - In the jejunum
What are the three P's of Parietal cells? Right Ans - 1. Pink
2. Produce protons (acid)
3. Pernicious anemia
What is a critical complication of Paroxysmal Nocturnal Hemoglobinuria?
Right Ans - Iron deficiency anemia and Acute Myeloid Leukemia
What is neutrophilic leukocytosis? What can cause it? Right Ans - Increased
numbers of circulating neutrophils
, Bacterial infection or tissue necrosis can cause this and many of these
circulating PMN's are immature (LEFT SHIFT): THESE IMMATURE CELLS ARE
CHARACTERIZED BY DECREASED Fc RECEPTORS (CD16)
What three things can cause Eosinophilia? Right Ans - 1. Type I HS Allergic
Reactions
2. Parasitic Infections
3. Hodgkin Lymphoma
What organism can cause a lymphocytic leukocytosis? How does it do this?
Right Ans - BORDETELLA PERTUSSIS
Bacteria produce lymphocytosis-promoting factor, which blocks circulating
lymphocytes from leaving the blood to enter the lymph node
What three locations does EBV primarily infect? Right Ans - 1. Oropharynx
2. Liver
3. B Cells
Kids who contract EBV should follow what recommendation? Why? Right
Ans - Avoid contact sports for 1 year
Increased risk for splenic rupture
What group represents the most common class of patients to develop Acute
Lymphoblastic Leukemia? Right Ans - Most commonly arises in children
and is associated with Down Syndrome that USUALLY DEVELOPS AFTER THE
AGE OF 5 YEARS -> "down syndrome kids always want ALL the hugs"
What are the two most common translocations that lead to ALL and what
groups are they seen in? Right Ans - t(12;21) has a good prognosis ->
commonly seen in children (especially Down syndrome patients after age 5)
t(9;22) has a poor prognosis -> commonly seen in adults (Philadelphia
chromosome)
How do you differentiate lymphoblasts from myeloblasts? Right Ans -
Lymphoblasts = TdT (+)
Myeloblasts = MPO (+)
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller LeCrae. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $13.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
82956 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now