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Neuropharmacology Advanced Pharm NURS8024 Exam 3|114 Questions with Verified Answers,100% CORRECT
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Neuropharmacology Advanced Pharm NURS8024 Exam 3|114 Questions with Verified Answers
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Neuropharmacology Advanced Pharm NURS8024 Exam 3|114 Questions with Verified Answers
In Parkinson's disease the amount of __________ lost directly correlates to
severity of symptoms. - CORRECT ANSWER Dopamine
The goal of treatment for Parkinson's disease is to CURE and REVERSE
degeneration. T / F - CORRECT ANSWER False - Tx focus is on restoring balance
Sinamet (Levodopa & Carbidopa) MOA includes: - CORRECT ANSWER Assist in
conversion of levodopa to dopamine in the basal nigra - Increase in body's
production of dopamine
How does Carbidopa help in Parkinson's disease? - CORRECT ANSWER Carbidopa
enhances availability of levodopa to cross the BBB. Decrease metabolism of
levodopa in the GI system
An NP understand that treatment effectiveness _____________ between the 3rd
and 5th year of Parkinson treatment using sinemet. - CORRECT ANSWER
Decreases
Important Pt Ed on Levodopa: - CORRECT ANSWER Take on an Empty Stomach
ADE with Levodopa include: - CORRECT ANSWER CNS effects (Visual/Auditory
Hallucinations, AIM, depression, GI effects, Tachy, Acute glaucoma
Amantadine is used to treat? - CORRECT ANSWER MINOR Parkinsons
MOA for Amantadine includes: - CORRECT ANSWER Enhances dopaminergic
neurotransmission, muscarininc blocking
An NP would be cautious in prescribing Amantadine for minor Parkinson's in a
patient with what dx? - CORRECT ANSWER Seizure D/O & CHF
, Name two dopamine receptor agonists: - CORRECT ANSWER Ropinirole &
Pramipexole
Name the one anticholingeric for EPS / Parkinsons - CORRECT ANSWER Cogentin /
Benzotropine
ADE of dopamine receptor agonists include: - CORRECT ANSWER GI, Postural
HYPO, Dyskinesias, confusion, delusions, hallucinations, IMPULSIVITY
Ropinirole and Pramipexole CAUSE: - CORRECT ANSWER IMPULSIVITY
Cogentin / Benzotropine is an________________ drug - CORRECT ANSWER
Anticholinergic
MAO-B Inbhitors - CORRECT ANSWER Monamine Oxidase B Inhibitors
When prescribing MAO-B Inhibitors use CAUTION with what two medications? -
CORRECT ANSWER Fluoxetine or Meperidine (Prozac or Demerol)
MAO-B Inhibitors include: - CORRECT ANSWER Selegiline (Eldepryl) & Rasagiline
(Azilect)
Use MAO-B Inhibitors _____________ and adjunct with __________. - CORRECT
ANSWER Early ; Levodopa
COMT (Catehcol-O-Methyltransferase Inhibitors) - CORRECT ANSWER Help with
uptake of Levodopa which increases dopamine in CNS
CAUTION when using _______________ & ___________ as both are major
enzymes that metabolize catecholamines. - CORRECT ANSWER MAO-B and COMT
Anticholinergics in Parkinson's disease are prescribed because........ - CORRECT
ANSWER Decrease Tremors
Decrease Rigidity
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