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ASCP PRACTICE (MB) EXAM QUESTION AND CORRECT ANSWER () 100% COMPLETE PASS

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ASCP PRACTICE (MB) EXAM QUESTION AND CORRECT ANSWER () 100% COMPLETE PASS Question 1 Which of the following is not a component of a nucleotide?

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  • October 6, 2024
  • 45
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • ASCP PRACTICE
  • ASCP PRACTICE
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ASCP PRACTICE (MB) EXAM QUESTION AND CORRECT
ANSWER (2024-2025) 100% COMPLETE PASS



Question 1

Which of the following is not a component of a nucleotide?

Phosphate group

Anti-codon

Ribose sugar

Nitrogen base

Anti-codon



Question 2

According to Chargaff's rule of base pairing, adenine pairs with:

Thymine



Question 3

What genes would be screened in a breast cancer panel?

HER2, ERBB2, BRCA1



Question 4

Next Generation Sequencing uses:

Short sequence reads


ASCP PRACTICE (MB) EXAM

,Question 5

Purines and pyrimidines differ from each other in that:

Purines have two rings; pyrimidines have one ring



Question 6

The purines are:

Cytosine and uracil

Adenine and thymine

Thymine and cytosine

Adenine and guanine

Adenine and guanine



Question 7

What is the rate of mutation per round of DNA replication?

1 in 1,000 base pairs

1 in 10,000 base pairs

1 in 1,000,000 base pairs

1 in 1,000,000,000 base pairs

1 in 1,000,000,000 base pairs



Question 8

The rate of DNA migration through an agarose gel during electrophoresis does not depend on which
of the following factors?

Net charge of the molecule

Size of the molecule

Shape of the molecule

Nucleotide sequence of the molecule

Nucleotide sequence of the molecule


ASCP PRACTICE (MB) EXAM

,Question 9

What are the phases in a qPCR Amplification Plot?

Initiation, exponential, plateau

Baseline, exponential, plateau

Baseline, threshold, exponential, plateau

Baseline, initiation, threshold, exponential, plateau

Initiation, exponential, plateau



Question 10

Find the palindrome in this restriction enzyme site: 5'-CTGCAG-3'?



5'-GAC

3'-GAC

3'-CTG

5'-GTC

3'-GAC



Question 11

A patient with impaired judgment, personality changes, signs of abnormal body movements and
depression comes to the physician's office for a follow-up visit. The physician suspects a single-gene
disorder may be the cause of those clinical manifestations. A blood specimen was then sent to your
clinical laboratory for mutation screening in the Huntington gene. Testing with standard PCR indicates
that patient has Huntington Disease, HD. Which of the following would be consistent with this
diagnosis?

25 CAG repeats in the Huntington gene

85 CAG repeats in the Huntington gene

25 CGA repeats in the Huntington gene

85 CGA repeats in the Huntington gene

85 CAG repeats in the Huntington gene



ASCP PRACTICE (MB) EXAM

, Question 12

Which two HPV types are responsible for most cases of cervical cancer?

16 and 18

31 and 59

16 and 58

44 and 59

16 and 18



Question 13

Replication forks, known as origins of DNA replication, are created by this enzyme:

Ligase

Taq Polymerase

Primase

Helicase

Helicase



Question 14

Mutation in what gene is associated with Fragile X syndrome?

FMR1



Question 15

Mantle cell lymphoma (MCL) is caused by what translocation?

t(11;14)



Question 16

This polymerase is involved in "initiation of DNA replication and has primase activity":

Pol α



ASCP PRACTICE (MB) EXAM

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