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NSG5003 Week 2 Quiz With Complete Solution A+ Graded

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NSG5003 Week 2 Quiz With Complete Solution A+ Graded...

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  • October 7, 2024
  • 28
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NSG5003
  • NSG5003
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Easton
NSG5003 Week 2 Quiz With Complete
Solution A+ Graded

Hypersensitivity is best defined as a(an) - ANSWER c.

Altered immunologic response to an antigen that results in disease



A hypersensitivity reaction that produces an allergic response is called: - ANSWER
Anaphylaxis



The common hay fever allergy is expressed through a reaction that is mediated by
which class of immunoglobulins? - ANSWER IgE



Which type of antibody is involved in type I hypersensitivity reaction? - ANSWER IgE



Blood transfusion reactions are a form of: - ANSWER Alloimmunity



Which leukocyte is activated in an IgE-mediated hypersensitivity reaction? - ANSWER c.

Eosinophils



The degranulation of mast cells in IgE-mediated hypersensitivity is caused by the action
of which of the following receptors? - ANSWER Histamine bound to H2



Atopic individuals are genetically predisposed to develop allergies because they have: -
ANSWER c.

More IgE



What is the mechanism that results in type II hypersensitivity reactions? - ANSWER d.

,Antibodies bind to the antigens on the cell surface.



When mismatched blood is given that causes ABO incompatibility, the erythrocytes are
lysed by - ANSWER a.

Complement-mediated cell lysis



When antibodies form against red blood cell antigens of the Rh system, the blood cells
are lysed by: - ANSWER Phagocytosis in the spleen



When the soluble antigens from infectious agents enter circulation, tissue damage
results from: - ANSWER d.

Neutrophil granules and toxic oxygen products



Target cell destruction in a type II hypersensitivity reaction occurs via the action of: -
ANSWER d.

Natural killer cells



Graves disease (hyperthyroidism) is an example of which type II hypersensitivity
reaction? - ANSWER Modulation



Type III hypersensitivity reactions are the result of which of the following? - ANSWER b.

Binding of antibodies to soluble antigens that were released into body fluids and
deposition of the immune complexes in the tissues



A type IV hypersensitivity reaction causes which result? - ANSWER .

The lymphokine-producing Th1 cells directly attack and destroy cellular targets



In a type III hypersensitivity reaction, the harmful effects after the immune complexes
that are deposited in tissues are a result of: - ANSWER Complement activation

, Raynaud phenomenon is a form of type III hypersensitivity reaction and is caused by: -
ANSWER a.

Immune complexes that are deposited in capillary beds, obstructing circulation



Deficiency of which of the following metals can lead to depression in function of both B
and T cells? - ANSWER Zinc



Sensitization of the maternal immune system against antigens expressed by the fetus is
an example of what type of reaction? - ANSWER Alloimmunity



Which disease results from the deposition of circulating immune complexes containing
an antibody against the host DNA in tissues? - ANS Systemic lupus erythematosus



Why does there occur a tissue damage in acute rejection following organ
transplantation? - ANS a.

Th1 cells secrete cytokines that activate the infiltrating macrophages; cytotoxic T cells
attack the endothelial cells directly in the transplanted tissue.



What type of blood cell would carry the carbohydrate antigens for blood type? -
ANSwER Erythrocytes



A person with blood type O would most likely have high titers of what anti-antibodies? -
ANSwER A and B



What class of immunoglobulins forms isohemagglutinins? - ANSwER IgM



An individual infected with a virus, fungus, or yeast would most likely lack or have
defective what immunological component? - ANSwER T cells



What is the primary immune deficiency in which T-cell immunity is partially or
completely absent? DiGeorge syndrome

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