NR 565 - advanced pharmacology FINAL - Chamberlain Practice EXAM
1. In which patient population is Metformin contraindi- C. Alcoholics
cated in?
A. Diabetics with HA1c < 7.0%
B. Patients older than 50
C. Alcoholics
D. Women suffering from infertility
2. What lab value suggests metformin might be con- A. eGFR <30
traindicated?
A. eGFR <30
B. Crea 0.8
C. WBC 7.8
D. Bun 17
3. What medication is contraindicated to treat diabetes B. Thiazolidine-
if a patient already has a cardiac ejection fraction rate diones
of 40%?
A. Second Generation sulfonyureas
B. Thiazolidinediones
C. Dopamine Agonist
D. Glucosidase Inhibitor
4. Sabrina is a 35-year-old female who presents with A. Methimazole
complaints of fatigue, anxiety, and palpitations. She
has a long history of obesity and reports that she
is happy that she has lost 23 pounds in the last
2 months. She also reports that she has trouble
sleeping and her husband complains that she is
keeping the house too cold. Physical exam reveals
slight tachycardia at 104 bpm and a slightly enlarged
thyroid. Thyroid testing reveals hyperthyroidism or
Grave's disease.
Which of the following agents is the first-line treat-
ment for hyperthyroidism or Grave's disease?
A. Methimazole
, NR 565 - advanced pharmacology FINAL - Chamberlain Practice EXAM
B. Metoprolol
C. Allopurinol
D. Levothyroxine
5. Which of the following medications would be consid- C: Oral Metformin
ered the first line of treatment for a newly diagnosed
Diabetic patient with adequate renal and hepatic func-
tion?
6. Of the following medications, which is most likely to B. Insulin
cause hypoglycemia?
A. Metformin
B. Insulin
C. Incretin mimetics
D. Thiazolidinediones
7. Which symptoms are most expected of a patient diag- D. dry skin, brit-
nosed with hypothyroidism? tle hair, fatigue,
myxedema
A. shortness of breath, wheezing, fatigue
B. tachycardia, insomnia, weight loss, goiter
C. irritability, anxiety, dizziness, increased sweating
D. dry pale skin, brittle hair, fatigue, myxedema
8. Patients with an increased risk for UTIs and genital C. Sodium-Glu-
infections or an active diagnosis, should avoid what cose Cotrans-
drug class/es for treatment of Type II Diabetes? porter 2 (SGLT-2)
Inhibitors.
A. Thiazolidinediones (Glitazones)
B. Biguanide.
C. Sodium-Glucose Cotransporter 2 (SGLT-2) In-
hibitors.
D. All of the above.
, NR 565 - advanced pharmacology FINAL - Chamberlain Practice EXAM
9. A 45-year-old patient with a history of type 2 diabetes D. Metformin im-
presents to the clinic for a follow-up appointment. The proves insulin sen-
healthcare provider has prescribed metformin as part sitivity and re-
of the treatment plan. Which of the following state- duces hepatic glu-
ments regarding metformin is correct? cose production.
A. Metformin primarily stimulates insulin production
from the pancreas.
B. Metformin reduces glucose levels primarily by de-
creasing insulin resistance.
C. Metformin is associated with a risk of hypo-
glycemia.
D. Metformin improves insulin sensitivity and reduces
hepatic glucose production.
10. In what part of the body are SGLT-2 (sodium-glucose C. Renal tubules
cotransporter 2) inhibitors active?
A. Small intestine
B. Pancreas
C. Renal tubules
D. Stomach
11. Which of the following statements is not true regard- A. Sulonlyreas are
ing sulfonylureas? safe to prescribe
to pregnant and/or
A. Sulonlyreas are safe to prescribe to pregnant breast-feeding
and/or breast-feeding women. women.
B. Patients should be educated about signs and symp-
toms of hypoglycemia.
C. Sulfonylureas cause a dose-dependent reduction
in blood glucose.
D. Sulfonylureas are indicated for only patients diag-
nosed with type 2 diabetes.
12. A 33 year old woman previously diagnosed with hy- A. atenolol
perthyroidism noted have tachycardia. Which medica-
tion should the NP add to the patients regimen?
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