human immunodeficiency virus (HIV) was recognized as a new virus in ________ ? -
answer1980s
In 1986 two types of HIV were isolated as the virus that causes AIDS; these are
_______ __ and _______ __ . - answer HIV 1 and HIV 2
what is HIV 1 - answer The predominant type; easily transmissible; more progressive
what is HIV 2 - answer confined to west Africa
How is HIV transmitted ? - answer by exposure to body fluids that contain the virus, not
by lifestyle or sexual orientation
HIV causes AIDS; AIDS does not cause HIV - answer
who was the first population to be affected by HIV? - answerMSM (Men having sex with
Men)
- but then it was seen in other populations
How many people are living with HIV ? - answer1.1 Million
many of which do not know they are affected
Wat are the 5 primary transmission categories established when reporting HIV rates -
answer1. Male-to-Male sexual contact
2. Injection Drug Use
3. Male-to-Female sexual contact
4. Mother-to-Child (perinatal) transmission
5. Other (transfusions & unknown)
HIV can be found in LOW concentrations in: - answerSaliva
Tears
Urine
What type of virus is HIV ? - answerRETROVIRUS
what does HIV do to the cells ? - answerHIV causes the destruction of IMMUNE cells;
therefore the body cannot fight off anything anymore
, What happens to the genetic material when infected with HIV? - answerthe genetic
material is reversed
How HIV destroys the immune system - answerHIV contains 2 protein markers that
attach themselves to other protein markers found on macrophages and T4 helper cells,
especially mucous membranes and body orifices ----> once attached, it infuses its
genetic material to the host cell, inserting HIV DNA to the hosts DNA ----> billions of
copies of HIV are made -----> destroys T4 (CD4) helper cells ----> immune response is
severely impaired and opportunistic infections gain access.
Once infected, the body tries to defend itself with _____ and __ _____. -
answerAntibodies and T Cells
when can HIV be detected? - answerabout 12 weeks
what is detected in the early stages if HIV ? - answerhigh levels of viral blood
once sufficient antibodies are produced, viral load decreases which gives partial
effectiveness of the body to rid itself of HIV. The antibodies will continue to remain high,
but T Cells (CD4) continues to decline. - answer
Initial stage of HIV - answer4-8weeks
high levels of Virus in the blood
50% Flu like s/sx and 50% have no s/sx
Latent stage of HIV - answer2-12years
Virus is inactive in the resting host cells but replicating
Levels are high in lymph nodes but low in blood.
Asymptomatic
T Cells decline
Third stage if HIV - answer2-3years
Opportunistic infections
T Cells are at their lowest
CD4 levels fall below 200cells/mm3 Pt has AIDS
Virus levels in their blood are HIGH
what drug therapy is used? - answerHAART
Highly Active Antiretroviral Therapy
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